A0A0J1LPQ5 · A0A0J1LPQ5_9ENTR

  • Protein
    O-acetyl-ADP-ribose deacetylase
  • Gene
    ymdB
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Deacetylates O-acetyl-ADP ribose to yield ADP-ribose and free acetate. Down-regulates ribonuclease 3 (RNase III) activity. Acts by interacting directly with the region of the ribonuclease that is required for dimerization/activation.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site11-12substrate
Binding site25substrate
Binding site33-35substrate
Active site35Proton acceptor
Binding site122-126substrate

GO annotations

AspectTerm
Molecular FunctionO-acetyl-ADP-ribose deacetylase activity
Molecular Functionpurine nucleoside binding
Molecular Functionribonuclease inhibitor activity
Biological Processnegative regulation of endoribonuclease activity
Biological Processpurine nucleoside metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    O-acetyl-ADP-ribose deacetylase
  • EC number
  • Alternative names
    • Regulator of RNase III activity

Gene names

    • Name
      ymdB
    • ORF names
      SK36_02540

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • MGH106
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Citrobacter > Citrobacter freundii complex

Accessions

  • Primary accession
    A0A0J1LPQ5

Proteomes

Interaction

Subunit

Homodimer. Interacts with RNase III.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-175Macro

Sequence similarities

Belongs to the YmdB family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    180
  • Mass (Da)
    19,080
  • Last updated
    2015-10-14 v1
  • Checksum
    AF080EF8E0DC2C73
MQSRVHVLHGDITTIAVDVIVNAANSSLLGGGGVDGAIHRAAGPALLEACKQVIQQQGECPTGHAVITLAGSLPAKAVIHTVGPVWQGGGHHEAERLEEAYLNTLQLALANGYQSIAFPAISTGAYGYPRAAAAEIAVNTVLKFITRRALPEQIYFVCFDDENTRLYNRLLTQQGDDHTA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LESQ01000002
EMBL· GenBank· DDBJ
KLV64504.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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