A0A0H3PIZ6 · A0A0H3PIZ6_ECO5C

Function

function

Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

FMN (UniProtKB | Rhea| CHEBI:58210 )

Note: Binds 1 FMN per subunit.

Pathway

Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate: step 1/1.
Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxine 5'-phosphate: step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site14-17substrate
Binding site67-72FMN (UniProtKB | ChEBI)
Binding site72substrate
Binding site82-83FMN (UniProtKB | ChEBI)
Binding site88FMN (UniProtKB | ChEBI)
Binding site89FMN (UniProtKB | ChEBI)
Binding site111FMN (UniProtKB | ChEBI)
Binding site129substrate
Binding site133substrate
Binding site137substrate
Binding site146-147FMN (UniProtKB | ChEBI)
Binding site191FMN (UniProtKB | ChEBI)
Binding site197-199substrate
Binding site201FMN (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular FunctionFMN binding
Molecular Functionpyridoxamine phosphate oxidase activity
Biological Processpyridoxine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Pyridoxine/pyridoxamine 5'-phosphate oxidase
  • EC number
  • Alternative names
    • PNP/PMP oxidase
      (PNPOx
      )
    • Pyridoxal 5'-phosphate synthase

Gene names

    • Name
      pdxH
    • ORF names
      ECH7EC869_0423

Organism names

Accessions

  • Primary accession
    A0A0H3PIZ6

Proteomes

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain39-122Pyridoxamine 5'-phosphate oxidase putative
Domain178-218Pyridoxine 5'-phosphate oxidase dimerisation C-terminal

Sequence similarities

Belongs to the pyridoxamine 5'-phosphate oxidase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    218
  • Mass (Da)
    25,561
  • Last updated
    2015-09-16 v1
  • Checksum
    95582F0EA6D83923
MSDNDELQQIAHLRREYTKGGLRRRDLPADPLTLFERWLSQACEAKLADPTAMVVATVDEHGQPYQRIVLLKHYDEKGMVFYTNLGSRKAHQIENNPRVSLLFPWHTLERQVMVIGKAERLSTLEVMKYFHSRPRDSQIGSWVSKQSSRISARGILESKFLELKQKFQQGEVPLPSFWGGFRVSLEQIEFWQGGEHRLHDRFLYQRENDAWKIDRLAP

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
ABHU01000023
EMBL· GenBank· DDBJ
EDU89360.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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