A0A0H3NM73 · PNP_SALTS

Function

function

Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity).
Involved in decay of speF mRNA (PubMed:30742606).

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site.

1711100200300400500600700
TypeIDPosition(s)Description
Binding site486Mg2+ (UniProtKB | ChEBI)
Binding site492Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Function3'-5'-RNA exonuclease activity
Molecular Functionmagnesium ion binding
Molecular Functionpolyribonucleotide nucleotidyltransferase activity
Molecular FunctionRNA binding
Biological ProcessmRNA catabolic process
Biological ProcessRNA processing

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Polyribonucleotide nucleotidyltransferase
  • EC number
  • Alternative names
    • Polynucleotide phosphorylase
      (PNPase
      )

Gene names

    • Name
      pnp
    • Ordered locus names
      SL1344_3255

Organism names

Accessions

  • Primary accession
    A0A0H3NM73

Proteomes

Subcellular Location

Keywords

Phenotypes & Variants

Disruption phenotype

Increased stability of speF mRNA.

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004503491-711Polyribonucleotide nucleotidyltransferase

Interaction

Subunit

Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.

Family & Domains

Features

Showing features for domain, region.

Type
IDPosition(s)Description
Domain553-612KH
Domain622-690S1 motif
Region690-711Disordered

Sequence similarities

Belongs to the polyribonucleotide nucleotidyltransferase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    711
  • Mass (Da)
    77,039
  • Last updated
    2015-09-16 v1
  • Checksum
    BCF7F15FC536A017
MLNPIVRKFQYGQHTVTLETGMMARQATAAVMVSMDDTAVFVTVVGQKKAKPGQDFFPLTVNYQERTYAAGRIPGSFFRREGRPSEGETLIARLIDRPVRPLFPEGFVNEVQVIATVVSVNPQVNPDIVAMIGASAALSLSGIPFNGPIGAARVGYINDQYVLNPTQDELKESKLDLVVAGTEAAVLMVESEAELLSEDTMLGAVVFGHEQQQVVIQAINDLVKEAGKPRWDWQPEAVNDALNARVAALAESRLSDAYRITDKQERYAQVDVIKSETIEQLIAEDETLDANELGEILHAIEKNVVRSRVLAGEPRIDGREKDMIRGLDVRTGVLPRTHGSALFTRGETQALVTATLGTARDAQVLDELMGERTDSFLFHYNFPPYSVGETGMVGSPKRREIGHGRLAKRGVLAVMPDMDKFPYTVRVVSEITESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEGDNYVVLSDILGDEDHLGDMDFKVAGSRDGISALQMDIKIEGITKEIMQVALNQAKGARLHILGVMEQAINAPRGDISEFAPRIHTIKISTDKIKDVIGKGGSVIRALTEETGTTIEIEDDGTVKIAATDGEKAKYAIRRIEEITAEIEVGRIYNGKVTRIVDFGAFVAIGGGKEGLVHISQIADKRVEKVTDYLQMGQEVPVKVLEVDRQGRVRLSIKEATEQSQPAAAPEAPASEQAE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FQ312003
EMBL· GenBank· DDBJ
CBW19351.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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