A0A0H3N116 · A0A0H3N116_MYCLB
- ProteintRNA-specific adenosine deaminase
- GenetadA
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids171 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
Catalytic activity
- adenosine34 in tRNA + H2O + H+ = inosine34 in tRNA + NH4+
RHEA-COMP:10373 CHEBI:74411 Position: 34+ CHEBI:15377 + CHEBI:15378 = RHEA-COMP:10374 CHEBI:82852 Position: 34+ CHEBI:28938
Cofactor
Note: Binds 1 zinc ion per subunit.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 66 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Active site | 68 | Proton donor | |||
Binding site | 97 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Binding site | 100 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | tRNA-specific adenosine-34 deaminase activity | |
Molecular Function | zinc ion binding | |
Biological Process | tRNA wobble adenosine to inosine editing |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nametRNA-specific adenosine deaminase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Mycobacteriaceae > Mycobacterium
Accessions
- Primary accessionA0A0H3N116
Proteomes
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 15-127 | CMP/dCMP-type deaminase | |||
Sequence similarities
Belongs to the cytidine and deoxycytidylate deaminase family. ADAT2 subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length171
- Mass (Da)17,974
- Last updated2015-09-16 v1
- Checksum2C8A8302FAD594EB
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
FM211192 EMBL· GenBank· DDBJ | CAR72573.1 EMBL· GenBank· DDBJ | Genomic DNA |