A0A0H3MR49 · A0A0H3MR49_MYCLB
- ProteinLarge ribosomal subunit assembly factor BipA
- GenebipA
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids628 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
Catalytic activity
- GTP + H2O = GDP + phosphate + H+
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 13-18 | GTP (UniProtKB | ChEBI) | |||
Binding site | 131-134 | GTP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Cellular Component | ribonucleoprotein complex | |
Molecular Function | GTP binding | |
Molecular Function | GTPase activity | |
Molecular Function | ribosome binding | |
Molecular Function | rRNA binding | |
Molecular Function | translation elongation factor activity | |
Molecular Function | tRNA binding | |
Biological Process | ribosomal large subunit assembly |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameLarge ribosomal subunit assembly factor BipA
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Mycobacteriaceae > Mycobacterium
Accessions
- Primary accessionA0A0H3MR49
Proteomes
Subcellular Location
Interaction
Subunit
Monomer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 1-215 | Tr-type G | |||
Sequence similarities
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length628
- Mass (Da)67,995
- Last updated2015-09-16 v1
- Checksum7020DA45A1DDFACF
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
FM211192 EMBL· GenBank· DDBJ | CAR71592.1 EMBL· GenBank· DDBJ | Genomic DNA |