A0A0H3HA88 · GSPI_KLEM8

Function

function

Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm (By similarity).
Part of the pseudopilus tip complex that is critical for the recognition and binding of secretion substrates (PubMed:22493189).

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentplasma membrane
Cellular Componenttype II protein secretion system complex
Biological Processprotein secretion by the type II secretion system

Names & Taxonomy

Protein names

  • Recommended name
    Type II secretion system protein I
  • Short names
    T2SS minor pseudopilin I
  • Alternative names
    • Putative general secretion pathway protein I

Gene names

    • Name
      pulI
    • Ordered locus names
      KOX_13590

Organism names

Accessions

  • Primary accession
    A0A0H3HA88

Proteomes

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane7-27Helical

Keywords

Phenotypes & Variants

Disruption phenotype

Deletion mutant shows longer pili but their number is reduced.

PTM/Processing

Features

Showing features for propeptide, modified residue, chain.

TypeIDPosition(s)Description
PropeptidePRO_00004495471-6Leader sequence
Modified residue7N-methylmethionine
ChainPRO_00004495487-121Type II secretion system protein I

Post-translational modification

Cleaved by prepilin peptidase.
Methylated by prepilin peptidase at the amino group of the N-terminal methionine once the leader sequence is cleaved by prepilin peptidase.

Keywords

Interaction

Subunit

Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus. Interacts with core component PulG (By similarity).
Interacts with pseudopilins PulJ and PulK (PubMed:22157749).

Family & Domains

Sequence similarities

Belongs to the GSP I family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    121
  • Mass (Da)
    13,721
  • Last updated
    2015-09-16 v1
  • Checksum
    BF5CA169F9B7E2E9
MNKQKGMTLLEVLVALAIFSLAGLTLLQTTAQQARNAGMMKEKMLASWLADNQQVRLHLNKLWPEKSATGALVTYAGEEWYLSWQGVDTEFSQLRALDIEVRRHKQDTAAIFSLRSYVVHE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP003218
EMBL· GenBank· DDBJ
AEX04442.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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