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A0A0H3CZI9 · A0A0H3CZI9_AMYMU

  • Protein
    1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
  • Gene
    hisA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Pathway

Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 4/9.

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site119Proton donor

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Function1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity
Molecular Functionphosphoribosylanthranilate isomerase activity
Biological ProcessL-histidine biosynthetic process
Biological Processtryptophan biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
  • EC number
  • Alternative names
    • Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase

Gene names

    • Name
      hisA
    • Ordered locus names
      AMED_2270

Organism names

Accessions

  • Primary accession
    A0A0H3CZI9

Proteomes

Subcellular Location

Keywords

Family & Domains

Sequence similarities

Belongs to the HisA/HisF family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    235
  • Mass (Da)
    24,489
  • Last updated
    2015-09-16 v1
  • MD5 Checksum
    CF9F054B085E3361231254CB2771A504
MADGQAVRLVQGEAGTETSYGSPLEAALAWQRDGAEWIHLVDLDAAFGKGSNRELLAEVVGRLDVQVELSGGIRDDASLKAALDTGARRVNLGTAALEDPEWTSRVIGEYGDRVAIGLDVRITEAGHRLSARGWTSDGGDLWDVLERLDRDGASRYVVTDVSKDGTLRGPNLELLRDVVARTDAPVIASGGVSSVADLVALAGLAADGVEGSIVGKALYAGAFTLPEALAAVAKL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP002000
EMBL· GenBank· DDBJ
ADJ44067.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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