A0A0H2ZGW7 · DPPB_PSEAB

Function

function

Part of the ABC transporter DppABCDF involved in the uptake of various di/tripeptides (PubMed:25338022).
Is also involved in the uptake of phaseolotoxin, a toxic tripeptide inhibiting the enzyme ornithine carbamoyltransferase (PubMed:25338022).
Responsible for the translocation of the substrate across the membrane (Probable)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentplasma membrane
Biological Processpeptide transport
Biological Processprotein transport
Biological Processtransmembrane transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Di/tripeptide transport system permease protein DppB

Gene names

    • Name
      dppB
    • Ordered locus names
      PA14_58440

Organism names

Accessions

  • Primary accession
    A0A0H2ZGW7

Proteomes

Subcellular Location

Cell inner membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane10-30Helical
Transmembrane102-122Helical
Transmembrane145-165Helical
Transmembrane198-218Helical
Transmembrane257-277Helical
Transmembrane307-327Helical

Keywords

Phenotypes & Variants

Disruption phenotype

Deletion of the dppBCDF operon leads to reduced ability to utilize di/tripeptides as nitrogen source.

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004521941-336Di/tripeptide transport system permease protein DppB

Interaction

Subunit

The complex is composed of two ATP-binding proteins (DppD and DppF), two transmembrane proteins (DppB and DppC) and a solute-binding protein (DppA1-A5) (PubMed:25338022).
Five orthologous SBPs (DppA1-A5) are present in P.aeruginosa, which increases the substrate specificity of the DppBCDF transporter (PubMed:25338022).

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain96-325ABC transmembrane type-1

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    336
  • Mass (Da)
    37,073
  • Last updated
    2015-09-16 v1
  • Checksum
    DDEADC2DF1740C0B
MLSFIARRLGLLIPTFFGVTLLTFALIRLIPGDPVEVMMGERRVDPQMHAEALHRLGLDKPLYQQYLDYVGNLAQGNLGESLTTREGVWHEFLTLFPATLELSLAAMLFAGTFGLLAGVIAALKRGSLFDHGVMTVSLAGYSMPIFWWGLILIMLFSVSLGWTPVSGRLDLLYDIEPKTGFMLIDTLLSDEQGSFLDAVRHLILPAIVLGTIPLAVIARMTRSAMLEVLREDYVRTARAKGLSPARVVFVHALRNALIPVLTVFGLQVGTLLAGAVLTETIFSWPGIGKWLIDAISRRDYPVVQNGILLVATLVILVNFVVDILYGLANPRIRHQR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000438
EMBL· GenBank· DDBJ
ABJ13770.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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