A0A0H2UHW6 · A0A0H2UHW6_RAT
- ProteinMetabotropic glutamate receptor 5
- GeneGrm5
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids962 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Cellular Component | synapse | |
Molecular Function | G protein-coupled receptor activity | |
Biological Process | chemical synaptic transmission | |
Biological Process | phospholipase C-activating G protein-coupled glutamate receptor signaling pathway |
Keywords
- Molecular function
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus
Accessions
- Primary accessionA0A0H2UHW6
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 371-394 | Helical | ||||
Sequence: IAAVVFACLGLLATLFVTVIFIIY | ||||||
Transmembrane | 406-429 | Helical | ||||
Sequence: ELCYIILAGICLGYLCTFCLIAKP | ||||||
Transmembrane | 477-504 | Helical | ||||
Sequence: FMSACAQLVIAFILICIQLGIIVALFIM | ||||||
Transmembrane | 530-549 | Helical | ||||
Sequence: VVTPLGYNGLLILSCTFYAF | ||||||
Transmembrane | 561-583 | Helical | ||||
Sequence: AKYIAFTMYTTCIIWLAFVPIYF | ||||||
Transmembrane | 589-616 | Helical | ||||
Sequence: IITMCFSVSLSATVALGCMFVPKVYIIL |
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 369-631 | G-protein coupled receptors family 3 profile | ||||
Sequence: EPIAAVVFACLGLLATLFVTVIFIIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFILICIQLGIIVALFIMEPPDIMHDYPSIREVYLICNTTNLGVVTPLGYNGLLILSCTFYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITMCFSVSLSATVALGCMFVPKVYIILAKPERNVRSAFTTST | ||||||
Region | 660-683 | Disordered | ||||
Sequence: GSSGETLSSNGKSVTWAQNEKSTR | ||||||
Compositional bias | 695-710 | Polar residues | ||||
Sequence: INKKENPNQTAVIKPF | ||||||
Region | 695-729 | Disordered | ||||
Sequence: INKKENPNQTAVIKPFPKSTENRGPGAAAGGGSGP | ||||||
Region | 762-813 | Disordered | ||||
Sequence: EESFPAAARPRSPSPISTLSHLAGSAGRTDDDAPSLHSETAARSSSSQGSLM | ||||||
Compositional bias | 799-813 | Polar residues | ||||
Sequence: SETAARSSSSQGSLM | ||||||
Region | 881-941 | Disordered | ||||
Sequence: GAQGATGVSPAQETPTGAESAPGKPDLEELVALTPPSPFRDSVDSGSTTPNSPVSESALCI | ||||||
Compositional bias | 920-939 | Polar residues | ||||
Sequence: RDSVDSGSTTPNSPVSESAL |
Sequence similarities
Belongs to the G-protein coupled receptor 3 family.
Keywords
- Domain
Family and domain databases
Protein family/group databases
Sequence
- Sequence statusComplete
- Length962
- Mass (Da)105,117
- Last updated2015-09-16 v1
- Checksum8FFA5DAAE500C563
Computationally mapped potential isoform sequences
There are 2 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
P31424 | GRM5_RAT | Grm5 | 1203 | ||
A0A0H2UHN1 | A0A0H2UHN1_RAT | Grm5 | 994 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 695-710 | Polar residues | ||||
Sequence: INKKENPNQTAVIKPF | ||||||
Compositional bias | 799-813 | Polar residues | ||||
Sequence: SETAARSSSSQGSLM | ||||||
Compositional bias | 920-939 | Polar residues | ||||
Sequence: RDSVDSGSTTPNSPVSESAL |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AABR07004706 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AABR07004707 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AABR07004708 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AABR07004709 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AABR07004710 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AABR07004711 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AABR07004712 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |