A0A0G9H2D7 · A0A0G9H2D7_9GAMM
- ProteinFluoride-specific ion channel FluC
- GenefluC
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids127 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
Catalytic activity
- fluoride(in) = fluoride(out)This reaction proceeds in the forward direction.
Activity regulation
Na+ is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 76 | Na+ (UniProtKB | ChEBI); structural | |||
Binding site | 79 | Na+ (UniProtKB | ChEBI); structural | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | fluoride channel activity | |
Molecular Function | metal ion binding | |
Biological Process | cellular detoxification of fluoride |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameFluoride-specific ion channel FluC
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Lysobacterales > Rhodanobacteraceae > Dyella
Accessions
- Primary accessionA0A0G9H2D7
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 40-59 | Helical | |||
Transmembrane | 66-84 | Helical | |||
Transmembrane | 104-126 | Helical | |||
Keywords
- Cellular component
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length127
- Mass (Da)13,479
- Last updated2015-09-16 v1
- Checksum8EDD7FDE933471C2
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JPLA01000026 EMBL· GenBank· DDBJ | KLD63703.1 EMBL· GenBank· DDBJ | Genomic DNA |