A0A0G8XVR7 · A0A0G8XVR7_XANPE

  • Protein
    Aspartate 1-decarboxylase
  • Gene
    panD
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

pyruvate (UniProtKB | Rhea| CHEBI:15361 )

Note: Binds 1 pyruvoyl group covalently per subunit.

Pathway

Cofactor biosynthesis; (R)-pantothenate biosynthesis; beta-alanine from L-aspartate: step 1/1.

Features

Showing features for active site, binding site.

TypeIDPosition(s)Description
Active site25Schiff-base intermediate with substrate; via pyruvic acid
Binding site57substrate
Active site58Proton donor
Binding site73-75substrate

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionaspartate 1-decarboxylase activity
Biological Processalanine biosynthetic process
Biological Processpantothenate biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

Gene names

    • Name
      panD
    • ORF names
      DB769_21180
      , E2P68_23175
      , G3W61_12140

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • GEV2132
    • ALS7E
    • Xp_Tom_Tuscaloosa_18b
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Lysobacterales > Lysobacteraceae > Xanthomonas

Accessions

  • Primary accession
    A0A0G8XVR7

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain, modified residue.

TypeIDPosition(s)Description
ChainPRO_50426225091-24Aspartate 1-decarboxylase beta chain
Modified residue25Pyruvic acid (Ser)
ChainPRO_504262250825-126Aspartate 1-decarboxylase alpha chain

Post-translational modification

Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

Keywords

Interaction

Subunit

Heterooctamer of four alpha and four beta subunits.

Family & Domains

Sequence similarities

Belongs to the PanD family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    126
  • Mass (Da)
    13,637
  • Last updated
    2015-09-16 v1
  • Checksum
    64EC1BF390E58624
MHLSLLKAKIHRATVTHSELNYEGSIAIDGLLLEATGIREFEQVHIWDVTNGARFSTYAIRAEEGSGIMSLNGGAARHVQVGDLIIVAAFASMSEDEAKTFKPNLVYVNAHNAISHTNHSIPTQAA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAAGYU010000049
EMBL· GenBank· DDBJ
NEL76991.1
EMBL· GenBank· DDBJ
Genomic DNA
PUUL01000146
EMBL· GenBank· DDBJ
RXD49366.1
EMBL· GenBank· DDBJ
Genomic DNA
SMVF01000060
EMBL· GenBank· DDBJ
TVS46775.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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