A0A0G8WGM6 · A0A0G8WGM6_XANPE

  • Protein
    Glycerol-3-phosphate dehydrogenase [NAD(P)+]
  • Gene
    gpsA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the reduction of the glycolytic intermediate dihydroxyacetone phosphate (DHAP) to sn-glycerol 3-phosphate (G3P), the key precursor for phospholipid synthesis.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Membrane lipid metabolism; glycerophospholipid metabolism.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site12-17NAD+ (UniProtKB | ChEBI)
Binding site15NADPH (UniProtKB | ChEBI)
Binding site16NADPH (UniProtKB | ChEBI)
Binding site36NADPH (UniProtKB | ChEBI)
Binding site53NADPH (UniProtKB | ChEBI)
Binding site110NADPH (UniProtKB | ChEBI)
Binding site110sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site110substrate
Binding site139sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site141sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site143NAD+ (UniProtKB | ChEBI)
Binding site143NADPH (UniProtKB | ChEBI)
Active site194Proton acceptor
Binding site194sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site247sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site257sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site258NAD+ (UniProtKB | ChEBI)
Binding site258NADPH (UniProtKB | ChEBI)
Binding site258sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site258-259substrate
Binding site259sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site282NADPH (UniProtKB | ChEBI)
Binding site284NADPH (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionglycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Molecular FunctionNAD binding
Biological Processcarbohydrate metabolic process
Biological Processglycerol-3-phosphate biosynthetic process
Biological Processglycerol-3-phosphate catabolic process
Biological Processglycerophospholipid metabolic process
Biological Processphospholipid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glycerol-3-phosphate dehydrogenase [NAD(P)+]
  • EC number
  • Alternative names
    • NAD(P)(+)-dependent glycerol-3-phosphate dehydrogenase
    • NAD(P)H-dependent dihydroxyacetone-phosphate reductase

Gene names

    • Name
      gpsA
    • ORF names
      DB769_07940
      , G3W61_07605
      , IPT11_08380
      , LN547_00780

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • GEV2132
    • Xp_Tom_Tuscaloosa_18b
    • JK68-3
    • Xv 1484
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Lysobacterales > Lysobacteraceae > Xanthomonas

Accessions

  • Primary accession
    A0A0G8WGM6

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain7-163Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Domain183-321Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    341
  • Mass (Da)
    35,858
  • Last updated
    2015-09-16 v1
  • Checksum
    7780E4AA745DB071
MSDWTHKIAVLGAGSWGTALAALLARHGHPTVLWGRDAAMVDTIDRTHENARYLPGIALPDSLRATTDLQAAVADATWILVVVPSHAFTETIRLIAPLRPAGAGVAWATKGFEPGSGRFLHEVARDILGPSVPLAVVTGPSFAKEVTLGLPTAITVHGDDAAFAQVVADAMHGPTFRAYTGDDMVGAELGGAMKNVLAVATGVADGMQLGLNARAGLITRGLNEMLRLAAVIGARPETLMGLAGLGDLVLTCTGDLSRNRRLGLALGRGQSLDDAIREIGQVVESVQTADEVMRQAEHHGIELPISNAVRAVLHGEITPEAGLKELLARERKPEYPQTLFT

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JADETX010000003
EMBL· GenBank· DDBJ
MBZ2450338.1
EMBL· GenBank· DDBJ
Genomic DNA
JAJITY010000004
EMBL· GenBank· DDBJ
MCC8560666.1
EMBL· GenBank· DDBJ
Genomic DNA
JAAGYU010000024
EMBL· GenBank· DDBJ
NEL76116.1
EMBL· GenBank· DDBJ
Genomic DNA
PUUL01000038
EMBL· GenBank· DDBJ
RXD54893.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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