A0A0G8TT39 · A0A0G8TT39_XANPE
- ProteinPimeloyl-[acyl-carrier protein] methyl ester esterase
- GenebioH
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids253 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.
Catalytic activity
- 6-carboxyhexanoyl-[ACP] methyl ester + H2O = 6-carboxyhexanoyl-[ACP] + H+ + methanol
Pathway
Cofactor biosynthesis; biotin biosynthesis.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 18 | substrate | ||||
Sequence: W | ||||||
Active site | 78 | Nucleophile | ||||
Sequence: S | ||||||
Binding site | 78-79 | substrate | ||||
Sequence: SL | ||||||
Binding site | 139-143 | substrate | ||||
Sequence: FLALD | ||||||
Active site | 203 | |||||
Sequence: D | ||||||
Active site | 231 | |||||
Sequence: H | ||||||
Binding site | 231 | substrate | ||||
Sequence: H |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | carboxylic ester hydrolase activity | |
Biological Process | biotin biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePimeloyl-[acyl-carrier protein] methyl ester esterase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Lysobacterales > Lysobacteraceae > Xanthomonas
Accessions
- Primary accessionA0A0G8TT39
Proteomes
Subcellular Location
Interaction
Subunit
Monomer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 10-237 | AB hydrolase-1 | ||||
Sequence: PALVLLHGWALHGGVFAPLVERLAPHYQLHLVDLPGHGFSRDDSTPLALPYVVAEIAAATPPAVWLGWSLGGLFALHAAATLPQVRGLAMIAATPRFVRGNDWPSAVQREVFVQFGIELSRDYRGTLERFLALDTLGSAHARSELRSLRETLTARGEPAPEALQQGLALLERTDLRRAVPQLARPSLWIAGQRDRLVPAAGMHAAAALSPHAQALTIAGGGHAPFLGH |
Sequence similarities
Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length253
- Mass (Da)27,049
- Last updated2015-09-16 v1
- Checksum1B939E0C0558C89F
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JADETX010000004 EMBL· GenBank· DDBJ | MBZ2450505.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JAJITY010000059 EMBL· GenBank· DDBJ | MCC8563574.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JAAGYU010000128 EMBL· GenBank· DDBJ | NEL78395.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
PUUL01000065 EMBL· GenBank· DDBJ | RXD53477.1 EMBL· GenBank· DDBJ | Genomic DNA |