A0A0G8TT39 · A0A0G8TT39_XANPE

  • Protein
    Pimeloyl-[acyl-carrier protein] methyl ester esterase
  • Gene
    bioH
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Pathway

Cofactor biosynthesis; biotin biosynthesis.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site18substrate
Active site78Nucleophile
Binding site78-79substrate
Binding site139-143substrate
Active site203
Active site231
Binding site231substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functioncarboxylic ester hydrolase activity
Biological Processbiotin biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Pimeloyl-[acyl-carrier protein] methyl ester esterase
  • EC number
  • Alternative names
    • Biotin synthesis protein BioH
    • Carboxylesterase BioH

Gene names

    • Name
      bioH
    • ORF names
      DB769_12110
      , G3W61_19450
      , IPT11_09260
      , LN547_15825

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • GEV2132
    • Xp_Tom_Tuscaloosa_18b
    • JK68-3
    • Xv 1484
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Lysobacterales > Lysobacteraceae > Xanthomonas

Accessions

  • Primary accession
    A0A0G8TT39

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Monomer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain10-237AB hydrolase-1

Sequence similarities

Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    253
  • Mass (Da)
    27,049
  • Last updated
    2015-09-16 v1
  • Checksum
    1B939E0C0558C89F
MHIDVIGHGPALVLLHGWALHGGVFAPLVERLAPHYQLHLVDLPGHGFSRDDSTPLALPYVVAEIAAATPPAVWLGWSLGGLFALHAAATLPQVRGLAMIAATPRFVRGNDWPSAVQREVFVQFGIELSRDYRGTLERFLALDTLGSAHARSELRSLRETLTARGEPAPEALQQGLALLERTDLRRAVPQLARPSLWIAGQRDRLVPAAGMHAAAALSPHAQALTIAGGGHAPFLGHADQVSEALQRFVASVP

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JADETX010000004
EMBL· GenBank· DDBJ
MBZ2450505.1
EMBL· GenBank· DDBJ
Genomic DNA
JAJITY010000059
EMBL· GenBank· DDBJ
MCC8563574.1
EMBL· GenBank· DDBJ
Genomic DNA
JAAGYU010000128
EMBL· GenBank· DDBJ
NEL78395.1
EMBL· GenBank· DDBJ
Genomic DNA
PUUL01000065
EMBL· GenBank· DDBJ
RXD53477.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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