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A0A0G4PLG7 · A0A0G4PLG7_PENC3

Function

function

Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 1 Mg2+ ion per subunit.

Pathway

Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route I): step 2/2.

Features

Showing features for active site, binding site.

Type
IDPosition(s)Description
Active site69Phosphoserine intermediate
Binding site69Mg2+ (UniProtKB | ChEBI); via phosphate group
Binding site281Mg2+ (UniProtKB | ChEBI)
Binding site283Mg2+ (UniProtKB | ChEBI)
Binding site285Mg2+ (UniProtKB | ChEBI)
Binding site377-379substrate
Binding site502-506substrate
Binding site511substrate

GO annotations

AspectTerm
Molecular Functionmagnesium ion binding
Molecular Functionphosphoacetylglucosamine mutase activity
Biological Processcarbohydrate metabolic process
Biological ProcessUDP-N-acetylglucosamine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphoacetylglucosamine mutase
  • EC number
  • Short names
    PAGM
  • Alternative names
    • Acetylglucosamine phosphomutase
    • N-acetylglucosamine-phosphate mutase

Gene names

    • ORF names
      PCAMFM013_S021g000129

Organism names

  • Taxonomic identifier
  • Strain
    • FM 013
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Eurotiomycetes > Eurotiomycetidae > Eurotiales > Aspergillaceae > Penicillium

Accessions

  • Primary accession
    A0A0G4PLG7

Proteomes

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain63-92Alpha-D-phosphohexomutase alpha/beta/alpha
Domain123-175Alpha-D-phosphohexomutase alpha/beta/alpha
Domain187-288Phosphoacetylglucosamine mutase AMG1
Domain302-441Phosphoacetylglucosamine mutase AMG1
Domain457-531Alpha-D-phosphohexomutase C-terminal

Sequence similarities

Belongs to the phosphohexose mutase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    539
  • Mass (Da)
    58,625
  • Last updated
    2015-09-16 v1
  • MD5 Checksum
    76EC2841448E785981B5A32C28B8390C
MASPAVKKAITEAALQYTKPEGKVFEYGTAGFRMKADLLNTVVFAVGLLASLRSKKLSGQWIGVMVTASHNPAEDNGVKLVDPMGEMLEAEWEAYATKLANAPLDKIADVYDELVKEIDVKMTNPARVVFARDTRASGSRLVSVLNAALTATEVEFVDFKYMTTPQLHYVVRCKNTLGTQYEYGEPTEQGYYEKLANSFKKVMRGVKVQGSLTVDCANGVGGPKLRELMKYLEGIDIKIVNDDVINPDALNFDCGADYVKTKQRAPPSSKAAVLDRCASLDGDADRLVYYFQDESNVFRLLDGDRIATLAASFIGDLARNAGIASKLKIGVVQTAYANGASTDYIEKVLKLPIICTNTGVKHLHHAALRFDVGVYFEANGHGTVTFSENALKVIKNTEPQSPAQQHALESLQALTDLINQAVGDALSDALLVEAILAHKGWSPKEWLGTYTDLPSRLVRVEVNDRSIFKAYDAERKLESPPGLQGTIESLQSRYNKGRSFARASGTEDAVRVYAEAASRSEADDLATRVANAVSEAGSA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
HG793154
EMBL· GenBank· DDBJ
CRL27214.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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