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A0A0G4PEH4 · A0A0G4PEH4_PENC3

Function

function

Type-I myosin implicated in the organization of the actin cytoskeleton. Required for proper actin cytoskeleton polarization. At the cell cortex, assembles in patch-like structures together with proteins from the actin-polymerizing machinery and promotes actin assembly. Functions as actin nucleation-promoting factor (NPF) for the Arp2/3 complex. Plays an important role in polarized growth, spore germination, hyphal morphogenesis, and septal wall formation.

Features

Showing features for binding site.

112671002003004005006007008009001,0001,1001,200
TypeIDPosition(s)Description
Binding site143-150ATP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentactin cortical patch
Cellular Componentcell tip
Cellular Componentmyosin complex
Cellular Componentvesicle
Molecular Functionactin filament binding
Molecular FunctionATP binding
Molecular Functionhydrolase activity
Molecular Functionmicrofilament motor activity
Biological Processactin filament organization
Biological Processendocytosis
Biological Processvesicle transport along actin filament

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Myosin-1
  • Alternative names
    • Class I unconventional myosin
    • Type I myosin

Gene names

    • ORF names
      PCAMFM013_S012g000266

Organism names

  • Taxonomic identifier
  • Strain
    • FM 013
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Eurotiomycetes > Eurotiomycetidae > Eurotiales > Aspergillaceae > Penicillium

Accessions

  • Primary accession
    A0A0G4PEH4

Proteomes

Subcellular Location

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, compositional bias, domain.

Type
IDPosition(s)Description
Region1-41Disordered
Compositional bias8-22Basic and acidic residues
Domain50-729Myosin motor
Region602-624Actin-binding
Domain787-976TH1
Region958-1044Disordered
Compositional bias960-978Polar residues
Compositional bias1024-1044Pro residues
Region1056-1108Disordered
Compositional bias1078-1093Pro residues
Domain1093-1154SH3
Region1155-1267Disordered
Compositional bias1156-1173Pro residues
Compositional bias1189-1214Pro residues
Compositional bias1218-1242Polar residues

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,267
  • Mass (Da)
    138,981
  • Last updated
    2015-09-16 v1
  • MD5 Checksum
    FAF7384ED074F2ADA987BEE96F243102
MGQSRRPVGGEKKSRFGRSKAVADVGDGRQAGGKPKVRKAAFESSKKKEIGVSDLTLLSKISNEAINDNLKLRFEHDEIYTYIGHVLVSVNPFRDLGIYTDSVLDSYRGKNRLEVPPHVFGVAESAYYNMKSYKDNQCVIISGESGAGKTEAAKRIMQYIASVSGGGDSSIQQTKDMVLATNPLLESFGNAKTLRNNNSSRFGKYLELEFNANGEPVGANITNYLLEKSRVVGQITNERNFHIFYQLTKGAPQKYRDSFGLQQPQSYLYTSRSKCFDVPGIDDVAEFKDTLDAMRVIGMSDGEQDNVFRMLAAILWIGNVQFSEDDSGNATISDQSVVDFVAYLLEVDSAQVNKALTIRLMETARGGRRGSVYEVPLNRVQASAVRDALAKGIYFNLFDWIVERVNQSLTARGSITNSIGILDIYGFEIFEKNSFEQLCINYVNEKLQQIFIQLTLKAEQDEYAREQIKWTPIEYFDNKVVCSLIEDKRPPGVFAALNDACATAHADSGAADQTFVGRLNFLSQNPNFEGRQGQFIIKHYAGDVSYAVEGMTDKNKDQLLKDLLNLAQSSSNEFVHSLFPNQVNQDDKRRPPTAGDKIKASANDLVATLMKAQPSYIRTIKPNDNKAPREYTHGNVLHQIKYLGLQENVRIRRAGFAYRQTFDKFTERFYLLSPKTSYAGDYTWTGDVESGAKQILKDTRIPAEEYQMGITKVFVKTPETLFALEAMRDKYWHNMAIRIQRAWRNYLRYRIECAIRIQRFWRRMTGGLEIIKVRDQGHQVLQGRKERRRMSLLGSRRFLGDYLGVGNTGGPGEMIRNGAGISGSDEVIFSCRAELLVSKFGRSSKPVPRILVLTSRHVYIVAQSIENNQLVISAERTIPVGAIKSVSTSNLKDDWFSLVIGAQEPDPLINCIFKTEFFTHLTTVLRGSLTLKVGETIEYHKKPGKLATVKAVKDPAAGNVDSYKSSTIHTSAGEPPNSVSKPTPRAKAVAARPVTKGKLLRPGGPGGGPSKLSQAARRPVPAAQPLPRSTPQPAAVPQPAAQPRVVPQPRIVPQPVAAAAAAHSRNESYSSVRSSGSARAPPPPPPAAPPPASRKPSAKVKYDYNSDRANELSIVKGEIVEIVSKEGNGWWLCKNTTTSAQGWTPESYLEEVAVAPAPKPIPPPPPMAPRATPSPIPNGAGAAAAAKTKPAPPAPPAKRPNMAGRKPAPPPAPRDSAVSMQSGDSSGASGRGTPNSASNASLAGGLAEALRARQSAMQGKHDDDDEW

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias8-22Basic and acidic residues
Compositional bias960-978Polar residues
Compositional bias1024-1044Pro residues
Compositional bias1078-1093Pro residues
Compositional bias1156-1173Pro residues
Compositional bias1189-1214Pro residues
Compositional bias1218-1242Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
HG793145
EMBL· GenBank· DDBJ
CRL24656.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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