A0A0G3AAF2 · A0A0G3AAF2_9ACTN

Function

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

thiamine diphosphate (UniProtKB | Rhea| CHEBI:58937 )

Pathway

Carbohydrate metabolism; tricarboxylic acid cycle; succinyl-CoA from 2-oxoglutarate (dehydrogenase route): step 1/1.

GO annotations

AspectTerm
Cellular Componentcytosol
Cellular Componentoxoglutarate dehydrogenase complex
Molecular Functiondihydrolipoyllysine-residue succinyltransferase activity
Molecular Functionlyase activity
Molecular Functionmagnesium ion binding
Molecular Functionoxoglutarate dehydrogenase (succinyl-transferring) activity
Molecular Functionthiamine pyrophosphate binding
Biological Processtricarboxylic acid cycle

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Submitted names
    • Alpha-ketoglutarate decarboxylase
      (EC:4.1.1.71
      )

Gene names

    • Name
      kgd
    • ORF names
      ABB07_12750

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • NRRL8089
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Kitasatosporales > Streptomycetaceae > Streptomyces

Accessions

  • Primary accession
    A0A0G3AAF2

Proteomes

Subcellular Location

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for compositional bias, region, coiled coil, domain.

Type
IDPosition(s)Description
Compositional bias1-17Polar residues
Region1-25Disordered
Region64-143Disordered
Compositional bias87-128Pro residues
Coiled coil832-859
Domain921-1114Transketolase-like pyrimidine-binding
Region1239-1258Disordered

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,269
  • Mass (Da)
    138,866
  • Last updated
    2015-09-16 v1
  • Checksum
    0F21DA194FD7A703
MSPQSPSNPSVSTDDQAGKNPAAAFGPNEWLVDEIYQQYLQDPNSVDRAWWDFFADYKPGAPATPAAAGTAAAGAAETTSTAAPAQPAVPPAQPAAPAPQAAAPAAPAAAPKPAAAPAPAPAKPATPAQAPAQPKQAAPVAKAAAAAEGPELITLRGPAAAVAKNMNASLELPTATSVRAVPVKLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQAIKAMPSMNWSFGEKDGKPTLVKPPHVNLGLAIDLVKPNGDRQLVVAAIKKAETLNFFEFWQAYEDIVRRARDGKLTMDDFTGVTVSLTNPGGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQGTSQDTLNKLGISKVMTLTSTYDHRVIQGAASGEFLRQVANLLLGENGFYDDIFEALRIPYEPVRWLKDIDASHDDDVTKAARVFELIHSYRVRGHVMADTDPLEYRQRKHPDLDIVEHGLTLWDLEREFAVGGFAGKSMMKLRDILGVLRDSYCRTTGIEFMHIQDPKQRKWIQDRVERGHSKPEREEQLRILRRLNAAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAESRLDEVVIGMAHRGRLNVLANIVGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLVANPSHLEAVDPVLEGVARAKQDIINKGGTDFTVLPVAIHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHIVINNQVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQAFNKDVVIDLICYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQALQDYQGQLEKVFTEVREATSQPAAVDAQAPQDGFPVTVPTAVSAEVVKRIAESQVNIPENITVHPRLQPQLQRRAAMVEDGTIDWGMGETLAIGSLLLEGTPVRLAGQDSQRGTFGQRHAVLIDRETGEEYTPLQYLSEDQARLNVYNSLLSEYAAMGFEYGYSLARPESLVMWEAQFGDFTNGAQTVVDEFISSAEQKWGQTSGVVLLLPHGYEGQGPDHSSARPERFLQLCAQNNMTVAMPTLPSNYFHLLRWQVHNPHHKPLIVFTPKSMLRLKAAASKAEEFTTGEFRPVIGDSSVDPAAVRKVVFCAGKVYYDLEAERQKRGATDTAIIRIERLYPLPGAELQAEIKKYPNAEKYLWAQEEPANQGAWPFIALNLIDHLDLAVGADVPHGERLRRISRPHSSSPAVGSAKRHQAEQEQLVREVFEA

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1-17Polar residues
Compositional bias87-128Pro residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP011497
EMBL· GenBank· DDBJ
AKJ10851.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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