A0A0G2Z583 · A0A0G2Z583_9BACT

  • Protein
    Aspartate--tRNA ligase
  • Gene
    aspS
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Features

Showing features for binding site.

158850100150200250300350400450500550
TypeIDPosition(s)Description
Binding site175L-aspartate (UniProtKB | ChEBI)
Binding site221L-aspartate (UniProtKB | ChEBI)
Binding site221-223ATP (UniProtKB | ChEBI)
Binding site230ATP (UniProtKB | ChEBI)
Binding site446L-aspartate (UniProtKB | ChEBI)
Binding site481ATP (UniProtKB | ChEBI)
Binding site488L-aspartate (UniProtKB | ChEBI)
Binding site533-536ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionaspartate-tRNA ligase activity
Molecular FunctionATP binding
Molecular Functionnucleic acid binding
Biological Processaspartyl-tRNA aminoacylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Aspartate--tRNA ligase
  • EC number
  • Alternative names
    • Aspartyl-tRNA synthetase
      (AspRS
      )

Gene names

    • Name
      aspS
    • ORF names
      IX53_01890

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • SLHLJ1
  • Taxonomic lineage
    Bacteria > Thermotogota > Thermotogae > Kosmotogales > Kosmotogaceae > Kosmotoga

Accessions

  • Primary accession
    A0A0G2Z583

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region.

Type
IDPosition(s)Description
Domain144-554Aminoacyl-transfer RNA synthetases class-II family profile
Region199-202Aspartate

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    588
  • Mass (Da)
    66,887
  • Last updated
    2015-09-16 v1
  • MD5 Checksum
    239BB7E7BD9C92C3DF585E2365F4B635
MEKRTHNCGELRKKDVGKEVVLNGWVDRIRDLGGIKFVLLRDRYGYTQVVFNPEDKELYEKALSLSPEYVISIRGKVMERPQDAVNPKMPTGEIEVHAVSLSILSESQTPPIYVNIDDESSEELRLKYRYLDLRRPKMQRNLILRHKVVQAIRRFLNNLDFLEIETPVLTKSTPEGARDFLVPSRLKPGKFYALPQSPQLFKQLLMVAGLDRYYQIVKCYRDEDFRADRQPEFTQVDLEMSFVDEEDVFEVVEGMLKAALEEATGIELPDKFDRMTYDEAIDQYGSDRPDRRYGMELHDITDIFKSTGFRVISSSIETGGVVRAFKIQGLASRFTRKLIDQYTELAKSQGLGGLIWIKIENELKSSILKFCGEEVQSVAERLGAMNGDIIFVAVGERELVSKALGKVREKVIAEELPVAEGIDILWITEFPMFSFNEEEKRIEAEHHPFTMPDLNDLSRYKDTNPLKIKSRAYDLVINGYEIGSGSVRIHRQDIQNEIFKLIGLSDEEANKKFGFLLEAFKYGPPPHAGIALGLDRLVAILAGANSIRDVIAFPKTASGSDPMTGAPSEVSQQQLKELKLMLMDGRGE

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP011232
EMBL· GenBank· DDBJ
AKI96775.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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