A0A0G2STK4 · A0A0G2STK4_PETMA

Function

Catalytic activity

  • heme b(in) + ATP + H2O = heme b(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
    EC:7.6.2.5 (UniProtKB | ENZYME | Rhea)
  • pheophorbide a(in) + ATP + H2O = pheophorbide a(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • protoporphyrin IX(in) + ATP + H2O = protoporphyrin IX(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • uroporphyrin I(in) + ATP + H2O = uroporphyrin I(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • uroporphyrin III(in) + ATP + H2O = uroporphyrin III(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • coproporphyrin I(in) + ATP + H2O = coproporphyrin I(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • coproporphyrin III(in) + ATP + H2O = coproporphyrin III(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • coproporphyrinogen III(in) + ATP + H2O = coproporphyrinogen III(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.

GO annotations

AspectTerm
Cellular Componentearly endosome membrane
Cellular Componentextracellular region
Cellular ComponentGolgi membrane
Cellular Componentlysosomal membrane
Cellular Componentmelanosome membrane
Cellular Componentmitochondrial outer membrane
Cellular Componentmultivesicular body membrane
Molecular FunctionABC-type heme transporter activity
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular Functionheme binding

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-binding cassette sub-family B member 6
  • EC number
  • Alternative names
    • ABC-type heme transporter ABCB6

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Cyclostomata > Hyperoartia > Petromyzontiformes > Petromyzontidae > Petromyzon

Accessions

  • Primary accession
    A0A0G2STK4

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Early endosome membrane
Endoplasmic reticulum membrane
; Multi-pass membrane protein
Endosome membrane
; Multi-pass membrane protein
Golgi apparatus membrane
; Multi-pass membrane protein
Late endosome membrane
Lysosome membrane
Melanosome membrane
Mitochondrion outer membrane
; Multi-pass membrane protein
Secreted, extracellular exosome

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane25-44Helical
Transmembrane65-87Helical
Transmembrane99-120Helical
Transmembrane132-154Helical
Transmembrane174-192Helical
Transmembrane259-281Helical
Transmembrane379-402Helical
Transmembrane408-428Helical
Transmembrane499-517Helical
Transmembrane523-543Helical

Keywords

PTM/Processing

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain, region, compositional bias.

Type
IDPosition(s)Description
Domain262-552ABC transmembrane type-1
Domain586-820ABC transporter
Region819-857Disordered
Compositional bias827-841Basic and acidic residues

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    857
  • Mass (Da)
    94,905
  • Last updated
    2015-09-16 v1
  • Checksum
    124F871BCB0524AD
MLGPYCEGGRPVSEAWVDGGVSPCLYRTLCGAVPPGALLLLGAVQGVRFARRAVLMEPKFVPRSLLHRLQVLLTVAMAALAVAYGAYHGATARGGVAGSVVAYATLSAVGWAASLALLGLERRRALPGDRVRGHGAALLGFWGLAFAGDTVAFVSWSSELWWWRLGSSEQKVDFGLWLSRFVCGLALFILGLRAPGLPPRPYSVLINEGERDVEQARPLLGDAGAARAAPNASAWTDFRKKVRLLVPYMWPRGSVRLQLAVLLCLVMLAGERVVNVFVPLYYKNIVNDLTQEAPWSTVAWTVVTYVGLKFLQGGGAGSSGFISNLRTFVWIRVQQFTNREVQVQLFEHLHSLSLRWHLGRKTGEVLRSVDRGTSSINSLLSYIVFSILPTIVDIVIAIIYFVTFFNAWFGLIVFVCMCVYLGITIAITEWRTKYRREMNTKDNQSKSKAVDSLLNFETVKYYNAESYEVQRFNQTIVEYQDAEWKTNASLAVLNQAQNVVIALGLLAGSLLSASFVTHKKLQVGDFVLFGTYIIQLYVPLNWFGTYYRMIQSSFIDMENMFELFGEEKEVVDDVNAVSLHLAHGKVEFDNVSFNYVNGKDILKNVSFTVPSGKTIALVGPSGAGKSTVMRLLFRFYDVKSGCISIDGQDISKVKQKSLRQHIGVVPQDTVLFNDTIRNNIRYGRVTASDEEVEEAARAADIHDRILSFPDGYNTQVGERGLKLSGGEKQRVAIARTILKAPELILLDEATSALDTQTERNIQASLAKICANRTSVVIAHRLSTIINADQILVLQDGQIVERGRHDELLTKGGIYTDMWSKQSQEASSESDTETKDKSSEKLQPASRNPQRGHHAHHH

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias827-841Basic and acidic residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KM232921
EMBL· GenBank· DDBJ
AKC42136.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

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