A0A0G2QC16 · A0A0G2QC16_RAT

Function

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
FAD (UniProtKB | Rhea| CHEBI:57692 )

Mo-molybdopterin (UniProtKB | Rhea| CHEBI:71302 )

Note: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
[2Fe-2S] cluster (UniProtKB | Rhea| CHEBI:190135 )

[2Fe-2S] cluster (UniProtKB | Rhea| CHEBI:190135 )

Note: Binds 2 [2Fe-2S] clusters.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site45[2Fe-2S] cluster 1 (UniProtKB | ChEBI)
Binding site50[2Fe-2S] cluster 1 (UniProtKB | ChEBI)
Binding site53[2Fe-2S] cluster 1 (UniProtKB | ChEBI)
Binding site75[2Fe-2S] cluster 1 (UniProtKB | ChEBI)
Binding site115[2Fe-2S] cluster 2 (UniProtKB | ChEBI)
Binding site118[2Fe-2S] cluster 2 (UniProtKB | ChEBI)
Binding site150[2Fe-2S] cluster 2 (UniProtKB | ChEBI)
Binding site152[2Fe-2S] cluster 2 (UniProtKB | ChEBI)
Binding site263-270FAD (UniProtKB | ChEBI)
Binding site366FAD (UniProtKB | ChEBI)
Binding site428FAD (UniProtKB | ChEBI)
Binding site771Mo (UniProtKB | ChEBI) of Mo-molybdopterin (UniProtKB | ChEBI)
Binding site802Mo (UniProtKB | ChEBI) of Mo-molybdopterin (UniProtKB | ChEBI)
Binding site916Mo (UniProtKB | ChEBI) of Mo-molybdopterin (UniProtKB | ChEBI)
Binding site918substrate
Binding site1083Mo (UniProtKB | ChEBI) of Mo-molybdopterin (UniProtKB | ChEBI)
Active site1264Proton acceptor

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Function2 iron, 2 sulfur cluster binding
Molecular Functionaldehyde oxidase activity
Molecular FunctionFAD binding
Molecular Functioniron ion binding
Molecular FunctionNAD binding

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    aldehyde oxidase
  • EC number

Gene names

    • Name
      Aox4
    • Synonyms
      Aox3

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Brown Norway
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus

Accessions

  • Primary accession
    A0A0G2QC16

Proteomes

Organism-specific databases

Subcellular Location

Keywords

Expression

Gene expression databases

Interaction

Subunit

Homodimer.

Structure

3D structure databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain6-932Fe-2S ferredoxin-type
Domain235-420FAD-binding PCMH-type

Sequence similarities

Belongs to the xanthine dehydrogenase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,333
  • Mass (Da)
    147,842
  • Last updated
    2022-05-25 v2
  • Checksum
    9A44D7F031AEFB1F
MPSSSDELIFFVNGKKVIEKNPVPEMNLLFYVRKVLHLTGTKYSCGGGGCGACTVMISRYNPESKKIYHYPATACLVPVCSLHGAAVTTVEGVGSIKRRIHPVQERLAKCHGTQCGFCSPGMVMSIYTLLRNHPEPTPDQITEALGGNLCRCTGYRPIVESGKTFSPESSVCQMKGSGKCCMDLDEGCSESTKERMCTKLYNEDEFQPLDPSQEPIFPPELIRMAEDPHKRRLTFQGERTIWIMPVTLNDLLELKASYPEAPLVMGNTAVGPGMKFNNEFHPVFISPLGLPELNLVDTANSGVTIGARHSLAQMKDILHSLTLEQPKEKTKTHQALLKHLRTLAGPQIRNMATLGGHVVSRPDFSDLNPILAAGNATINVISKEGQRQIPLNGPFLERLPEASLKPEEVALSVFIPYSGQWQYVSGLRLAQRQENAFAIVNAGMSVEFEEGTNTIKDLQMLFGSVAPTVVSASQTCKQLIGRQWDDQMLSDACQLVLEEIRIPPDAEGGMVEYRRTLIISLLFKFYLKVRRWLSEMDPQKFPDIPEKFVSALDDLPIETPQGIQMFQCVDPNQPEQDPVGHPIMHQSGIKHATGEAKFVDDMPRINQELCLTVVTSTRAHAKITSIDVSEALAYPGVVDVITAEDVPGDNNHSGEIFYAQNEVICVGQIICTVAADTYIHAKEAAKRVKITYDDIEPAIITIEQALEHNSFLSSEKKIEQGNVDYAFKHVDHIIEGEIHVEGQEHFYMETQTILAIPQTEDKEMVLHVGTQFPTHVQEYVSAALKVPRNRIACQMKRTGGAFGGKVTKPALLGAVCAVAAHKTGRPIRFILDRSNDMLITAGRHPLLGKYKIGFMNNGKIKAADVEYYTNGGCTPDESEMVIEFIVLKSENAYHIPNFRCRGRACKTNLPSNTAFRGFGFPQATVVVEAYIAAVASKCNLLPEEIREINMYKQISKTAYKQTFNPEPLRRCWKECLQKSSFFARKQAAEEFNKNNYWKKKGLAVVPMKFSVAVPMAFYNQAAALVHIFLDGSVLLTHGGCELGQGLHTKMIQVASRELNIPKSYVHLVETSTVTVPNAVFTAGSMGADINGKAVQNACQTLLDRLQPIIKKNPKGKWEEWVKKAFEESISLSATGYFKGYQTNMDWEKEEGDPYPYYVYGAACSEVEVDCLTGAHKLLRTDIFMDAAFSINPALDIGQVEGAFIQGMGFYTIEELKYSPKGVLYSRGPDDYKIPTVTEIPEEFYVTMVRSRNPIAIYSSKGLGEAGMFLGSSVLFAIYDAVTTARKERGLSDIFPLNSPATPEVIRMACKDQFTDMIPRDDPSTFTPWSIHVS

Computationally mapped potential isoform sequences

There are 10 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q5QE79AOXD_RATAox41334
A0A0G2K1Z5A0A0G2K1Z5_RATAox31088
A0A8I6GM92A0A8I6GM92_RATAox3945
A0A8I6A9L1A0A8I6A9L1_RATAox3270
Q7TP79Q7TP79_RATAox3945
A0A8I5YBF0A0A8I5YBF0_RATAox31280
A0A8I5ZJJ1A0A8I5ZJJ1_RATAox31111
A0A1B0GWV6A0A1B0GWV6_RATAox31334
A0A1B0GWM7A0A1B0GWM7_RATAox41307
A0A8I5ZQJ3A0A8I5ZQJ3_RATAox31384

Keywords

Sequence databases

Genome annotation databases

Similar Proteins

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