A0A0G2KB75 · A0A0G2KB75_RAT
- ProteinTumor protein p53
- GeneTp53
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids174 (go to sequence)
- Protein existencePredicted
- Annotation score2/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | endoplasmic reticulum | |
Cellular Component | mitochondrial matrix | |
Cellular Component | PML body | |
Molecular Function | DNA binding | |
Molecular Function | DNA-binding transcription factor activity | |
Biological Process | apoptotic process | |
Biological Process | protein tetramerization | |
Biological Process | rhythmic process |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus
Accessions
- Primary accessionA0A0G2KB75
Proteomes
Organism-specific databases
Subcellular Location
PTM/Processing
Keywords
- PTM
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for region, domain, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-40 | Disordered | ||||
Sequence: MEDSQSDMSIELPLSQETFSCSSLAHPQPTTATGSPNSME | ||||||
Domain | 6-21 | p53 transactivation | ||||
Sequence: SDMSIELPLSQETFSC | ||||||
Compositional bias | 8-40 | Polar residues | ||||
Sequence: MSIELPLSQETFSCSSLAHPQPTTATGSPNSME | ||||||
Region | 54-93 | Disordered | ||||
Sequence: GPEEALQVSAPAAQEPGTEAPAPVAPASATPWPLSSSVPS | ||||||
Domain | 112-137 | p53 tetramerisation | ||||
Sequence: TIRGRERFEMFRELNEALELKDARAA | ||||||
Compositional bias | 134-149 | Basic and acidic residues | ||||
Sequence: ARAAEESGDSRAHSSY | ||||||
Region | 134-174 | Disordered | ||||
Sequence: ARAAEESGDSRAHSSYPKTKKGQSTSRHKKPMIKKVGPDSD |
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length174
- Mass (Da)18,791
- Last updated2022-05-25 v2
- Checksum194B41CA3092F009
Computationally mapped potential isoform sequences
There are 7 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
P10361 | P53_RAT | Tp53 | 391 | ||
A0A0G2JTP9 | A0A0G2JTP9_RAT | Tp53 | 265 | ||
A0A0G2KBB2 | A0A0G2KBB2_RAT | Tp53 | 386 | ||
A0A8I6AAP4 | A0A8I6AAP4_RAT | Tp53 | 390 | ||
A0A8I6AEF4 | A0A8I6AEF4_RAT | Tp53 | 406 | ||
A0A8L2R913 | A0A8L2R913_RAT | Tp53 | 385 | ||
A0A8I5ZQW3 | A0A8I5ZQW3_RAT | Tp53 | 364 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 8-40 | Polar residues | ||||
Sequence: MSIELPLSQETFSCSSLAHPQPTTATGSPNSME | ||||||
Compositional bias | 134-149 | Basic and acidic residues | ||||
Sequence: ARAAEESGDSRAHSSY |
Keywords
- Technical term