A0A0G2K9W7 · A0A0G2K9W7_RAT
- ProteinLDL receptor related protein 2
- GeneLrp2
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids4660 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Molecular Function | calcium ion binding | |
Biological Process | endocytosis |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus
Accessions
- Primary accessionA0A0G2K9W7
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Single-pass type I membrane protein
Keywords
- Cellular component
PTM/Processing
Features
Showing features for disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Disulfide bond | 28↔40 | |||||
Sequence: CGSGNFRCDNGYC | ||||||
Disulfide bond | 35↔53 | |||||
Sequence: CDNGYCIPASWRCDGTRDC | ||||||
Disulfide bond | 47↔62 | |||||
Sequence: CDGTRDCLDDTDEIGC | ||||||
Disulfide bond | 108↔120 | |||||
Sequence: CSAQQMTCSNGQC | ||||||
Disulfide bond | 115↔133 | |||||
Sequence: CSNGQCIPSEYRCDHVSDC | ||||||
Disulfide bond | 127↔142 | |||||
Sequence: CDHVSDCPDGSDERNC | ||||||
Disulfide bond | 152↔170 | |||||
Sequence: CANGACYNTSQRCDQKVDC | ||||||
Disulfide bond | 164↔179 | |||||
Sequence: CDQKVDCRDSSDEANC | ||||||
Disulfide bond | 183↔195 | |||||
Sequence: CSQKEFECGSGEC | ||||||
Disulfide bond | 190↔208 | |||||
Sequence: CGSGECILRAYVCDHDNDC | ||||||
Disulfide bond | 202↔217 | |||||
Sequence: CDHDNDCEDNSDERNC | ||||||
Disulfide bond | 222↔234 | |||||
Sequence: CGGHQFTCSNGQC | ||||||
Disulfide bond | 229↔247 | |||||
Sequence: CSNGQCINQNWVCDGDDDC | ||||||
Disulfide bond | 241↔256 | |||||
Sequence: CDGDDDCQDSGDEDGC | ||||||
Disulfide bond | 1025↔1037 | |||||
Sequence: CGSLSFPCNNGKC | ||||||
Disulfide bond | 1032↔1050 | |||||
Sequence: CNNGKCVPSFFRCDGVDDC | ||||||
Disulfide bond | 1044↔1059 | |||||
Sequence: CDGVDDCHDNSDEHQC | ||||||
Disulfide bond | 1086↔1101 | |||||
Sequence: CDRQNDCLDGSDEQNC | ||||||
Disulfide bond | 1110↔1122 | |||||
Sequence: CPSTSFTCDNHVC | ||||||
Disulfide bond | 1117↔1135 | |||||
Sequence: CDNHVCIPKDWVCDTDNDC | ||||||
Disulfide bond | 1129↔1144 | |||||
Sequence: CDTDNDCSDGSDEKNC | ||||||
Disulfide bond | 1150↔1162 | |||||
Sequence: CQPTQFRCPDHRC | ||||||
Disulfide bond | 1157↔1175 | |||||
Sequence: CPDHRCISPLYVCDGDKDC | ||||||
Disulfide bond | 1169↔1184 | |||||
Sequence: CDGDKDCADGSDEAGC | ||||||
Disulfide bond | 1208↔1223 | |||||
Sequence: CDGVYDCRDNSDEAGC | ||||||
Disulfide bond | 1272↔1284 | |||||
Sequence: CSPTHFLCDNGNC | ||||||
Disulfide bond | 1279↔1297 | |||||
Sequence: CDNGNCIYKAWICDGDNDC | ||||||
Disulfide bond | 1291↔1306 | |||||
Sequence: CDGDNDCRDMSDEKDC | ||||||
Disulfide bond | 2701↔2713 | |||||
Sequence: CNQLQFTCLNGHC | ||||||
Disulfide bond | 2708↔2726 | |||||
Sequence: CLNGHCINQDWKCDNDNDC | ||||||
Disulfide bond | 2742↔2754 | |||||
Sequence: CRSTAFTCGNGRC | ||||||
Disulfide bond | 2749↔2767 | |||||
Sequence: CGNGRCVPYHYRCDYYNDC | ||||||
Disulfide bond | 2761↔2776 | |||||
Sequence: CDYYNDCGDNSDEAGC | ||||||
Disulfide bond | 2789↔2807 | |||||
Sequence: CSNGRCIPLSYVCNGINNC | ||||||
Disulfide bond | 2908↔2920 | |||||
Sequence: CRASQFQCDNGRC | ||||||
Disulfide bond | 2915↔2933 | |||||
Sequence: CDNGRCISGNWVCDGDNDC | ||||||
Disulfide bond | 2995↔3007 | |||||
Sequence: CSAGEFSCANGRC | ||||||
Disulfide bond | 3002↔3020 | |||||
Sequence: CANGRCVRQSFRCDRRNDC | ||||||
Disulfide bond | 3014↔3029 | |||||
Sequence: CDRRNDCGDYSDERGC | ||||||
Disulfide bond | 3034↔3046 | |||||
Sequence: CHANQFTCQNGRC | ||||||
Disulfide bond | 3041↔3059 | |||||
Sequence: CQNGRCIPRFFVCDEDNDC | ||||||
Disulfide bond | 3077↔3089 | |||||
Sequence: CPLHQFRCDNGHC | ||||||
Disulfide bond | 3084↔3102 | |||||
Sequence: CDNGHCIEMGRVCNHVDDC | ||||||
Disulfide bond | 3096↔3111 | |||||
Sequence: CNHVDDCSDNSDEKGC | ||||||
Disulfide bond | 3555↔3567 | |||||
Sequence: CRLGQFQCRDGNC | ||||||
Disulfide bond | 3562↔3580 | |||||
Sequence: CRDGNCTSPQALCNARQDC | ||||||
Disulfide bond | 3596↔3608 | |||||
Sequence: CESNEWQCANKRC | ||||||
Disulfide bond | 3603↔3621 | |||||
Sequence: CANKRCIPQSWQCDSVNDC | ||||||
Disulfide bond | 3637↔3649 | |||||
Sequence: CRPGQFKCNNGRC | ||||||
Disulfide bond | 3644↔3662 | |||||
Sequence: CNNGRCIPQSWKCDVDNDC | ||||||
Disulfide bond | 3701↔3716 | |||||
Sequence: CNGFDDCRDNSDEQGC | ||||||
Disulfide bond | 3729↔3747 | |||||
Sequence: CANHHCIPLRWKCDGTDDC | ||||||
Disulfide bond | 3741↔3756 | |||||
Sequence: CDGTDDCGDNSDEENC | ||||||
Disulfide bond | 3761↔3773 | |||||
Sequence: CSESEFRCADQQC | ||||||
Disulfide bond | 3768↔3786 | |||||
Sequence: CADQQCIPSRWVCDQENDC | ||||||
Disulfide bond | 3780↔3795 | |||||
Sequence: CDQENDCGDNSDERDC | ||||||
Disulfide bond | 3800↔3812 | |||||
Sequence: CHPEHFQCTSGHC | ||||||
Disulfide bond | 3807↔3825 | |||||
Sequence: CTSGHCVPKALACDGRADC | ||||||
Disulfide bond | 3819↔3834 | |||||
Sequence: CDGRADCLDASDESAC | ||||||
Disulfide bond | 3844↔3856 | |||||
Sequence: CPAAMFECKNHVC | ||||||
Disulfide bond | 3851↔3869 | |||||
Sequence: CKNHVCIQSFWICDGENDC | ||||||
Disulfide bond | 3893↔3911 | |||||
Sequence: CDNSRCVYGHQLCNGVDDC | ||||||
Disulfide bond | 3930↔3942 | |||||
Sequence: CTDTEYKCSNGNC | ||||||
Disulfide bond | 3937↔3955 | |||||
Sequence: CSNGNCISQHYVCDNVNDC | ||||||
Disulfide bond | 3949↔3964 | |||||
Sequence: CDNVNDCGDLSDETGC | ||||||
Disulfide bond | 4403↔4412 | |||||
Sequence: CSSGYSGEYC |
Keywords
- PTM
Expression
Gene expression databases
Family & Domains
Features
Showing features for repeat.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Repeat | 435-477 | LDL-receptor class B | ||||
Sequence: HRVFWTDPMQEKVFSTDINGLNTQEILNVSVDTPENLAVDWIN | ||||||
Repeat | 478-520 | LDL-receptor class B | ||||
Sequence: NKLYLVETKVNRIDVVNLEGNQRVTLITENLGHPRGIALDPTV | ||||||
Repeat | 521-567 | LDL-receptor class B | ||||
Sequence: GYLFFSDWGSLSGQPKVERAFMDGSNRKDLVTTKVGWPAGITLDLVS | ||||||
Repeat | 568-612 | LDL-receptor class B | ||||
Sequence: KRVYWVDSRYDYIETVTYDGIQRKTVARGGSLVPHPFGISLFEEH | ||||||
Repeat | 795-836 | LDL-receptor class B | ||||
Sequence: RNLYWTDGGLKSVTVLRLADKSRRQIISNLNNPRSIVVHPTA | ||||||
Repeat | 881-924 | LDL-receptor class B | ||||
Sequence: SRLYWVDAFFDKIEHSTLDGLDRKRLGHVDQMTHPFGLTVFKDN | ||||||
Repeat | 1522-1564 | LDL-receptor class B | ||||
Sequence: RNLYWTDYALETIEVSKIDGSHRTVLISKNVTKPRGLALDPRM | ||||||
Repeat | 1567-1610 | LDL-receptor class B | ||||
Sequence: NVMFWSDWGHHPRIERASMDGTMRTVIVQEKIYWPCGLSIDYPN | ||||||
Repeat | 1611-1655 | LDL-receptor class B | ||||
Sequence: RLIYFMDAYLDYIEFCDYDGHNRRQVIASDLVLHHPHALTLFEDF | ||||||
Repeat | 1884-1931 | LDL-receptor class B | ||||
Sequence: GKLYWSDHGTDSGVPAKIASANMDGTSLKILFTGNLQHLEVVTLDIQE | ||||||
Repeat | 1932-1973 | LDL-receptor class B | ||||
Sequence: QKLYWAVTSRGVIERGNVDGTERMILVHHLAHPWGLVVYGSF | ||||||
Repeat | 2203-2246 | LDL-receptor class B | ||||
Sequence: RYLFWADYGQKPKIERSFLDCTNRTVLVSEGIVTPRGLAMDHDT | ||||||
Repeat | 2247-2290 | LDL-receptor class B | ||||
Sequence: GYIYWVDDSLDLIARIHLDGGESQVVRYGSRYPTPYGITVFGES | ||||||
Repeat | 2520-2563 | LDL-receptor class B | ||||
Sequence: GYMYWTDWGTNAKIERATLGGNFRVPIVNTSLVWPNGLALDLET | ||||||
Repeat | 2564-2605 | LDL-receptor class B | ||||
Sequence: DLLYWADASLQKIERSTLTGTNREVVVSTAFHSFGLTVYGQY | ||||||
Repeat | 3241-3283 | LDL-receptor class B | ||||
Sequence: KRLYWIDAEKQIIERMFLNKTNRETIINHRLRRAESLAVDWVS | ||||||
Repeat | 3335-3378 | LDL-receptor class B | ||||
Sequence: GHVYWADWGVHAYIGRIGMDGTNKSVIISTKIEWPNAITIDYTN | ||||||
Repeat | 3379-3421 | LDL-receptor class B | ||||
Sequence: DLLYWADAHLGYIEFSDLEGHHRHTVYDGSLPHPFALTIFEDT | ||||||
Repeat | 4156-4198 | LDL-receptor class B | ||||
Sequence: RHIYWSDAKSQRIEVATLDGRYRKWLITTQLDQPAAIAVNPKL | ||||||
Repeat | 4199-4242 | LDL-receptor class B | ||||
Sequence: GLMFWTDQGKQPKIESAWMNGEHRSVLVSENLGWPNGLSIDYLN | ||||||
Repeat | 4244-4285 | LDL-receptor class B | ||||
Sequence: DRVYWSDSKEDVIEAIKYDGTDRRLIINEAMKPFSLDIFEDK |
Sequence similarities
Belongs to the LDLR family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length4,660
- Mass (Da)519,319
- Last updated2015-07-22 v1
- ChecksumA529D99C8F72620F
Computationally mapped potential isoform sequences
There are 2 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
P98158 | LRP2_RAT | Lrp2 | 4660 | ||
A0A8I5ZRK6 | A0A8I5ZRK6_RAT | Lrp2 | 4678 |
Keywords
- Technical term