A0A0G2JYS4 · A0A0G2JYS4_RAT
- ProteinStress-activated protein kinase JNK
- GeneMapk9
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids398 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
function
Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.
Catalytic activity
- L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H+
Cofactor
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | JUN kinase activity | |
Molecular Function | protein serine kinase activity | |
Biological Process | rhythmic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameStress-activated protein kinase JNK
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus
Accessions
- Primary accessionA0A0G2JYS4
Proteomes
Organism-specific databases
PTM/Processing
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for domain, region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 26-306 | Protein kinase | |||
Region | 354-398 | Disordered | |||
Sequence similarities
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length398
- Mass (Da)45,042
- Last updated2022-05-25 v2
- MD5 Checksum9F30F8680373B1B9FB71A5F8810DA702
Computationally mapped potential isoform sequences
There are 7 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
P49186 | MK09_RAT | Mapk9 | 423 | ||
A0A8I6AND2 | A0A8I6AND2_RAT | Mapk9 | 397 | ||
A0A8I6ANM5 | A0A8I6ANM5_RAT | Mapk9 | 408 | ||
Q6P727 | Q6P727_RAT | Mapk9 | 381 | ||
A0A8I6GCT6 | A0A8I6GCT6_RAT | Mapk9 | 133 | ||
A0A8I6A503 | A0A8I6A503_RAT | Mapk9 | 390 | ||
D4A5V8 | D4A5V8_RAT | Mapk9 | 381 |
Keywords
- Technical term