A0A0G2JY43 · A0A0G2JY43_RAT
- ProteinAldehyde dehydrogenase
- GeneAldh3a2
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids483 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
Catalytic activity
- (2E)-hexadecenal + NAD+ + H2O = (E)-hexadec-2-enoate + NADH + 2 H+
- hexadecanoate + NADH + 2 H+ = hexadecanal + NAD+ + H2O
- 2,6,10,14-tetramethylpentadecanal + NAD+ + H2O = 2,6,10,14-tetramethylpentadecanoate + NADH + 2 H+
- 22-oxodocosanoate + NAD+ + H2O = docosanedioate + NADH + 2 H+
- octadecanal + NAD+ + H2O = octadecanoate + NADH + 2 H+
- octanal + NAD+ + H2O = octanoate + NADH + 2 H+
- tetradecanal + NAD+ + H2O = tetradecanoate + NADH + 2 H+
- heptanal + NAD+ + H2O = heptanoate + NADH + 2 H+
- a fatty aldehyde + NAD+ + H2O = a fatty acid + NADH + 2 H+
- decanal + NAD+ + H2O = decanoate + NADH + 2 H+
- dodecanoate + NADH + 2 H+ = dodecanal + NAD+ + H2O
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 207 | ||||
Active site | 241 | ||||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | endoplasmic reticulum membrane | |
Molecular Function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | |
Biological Process | cellular aldehyde metabolic process | |
Biological Process | fatty acid metabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameAldehyde dehydrogenase
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus
Accessions
- Primary accessionA0A0G2JY43
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Endoplasmic reticulum membrane ; Single-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 464-482 | Helical | |||
Keywords
- Cellular component
Expression
Gene expression databases
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Sequence
- Sequence statusComplete
- Length483
- Mass (Da)53,938
- Last updated2022-05-25 v2
- MD5 Checksum8D7A8B3350564C84DFA1502D986A5092
Computationally mapped potential isoform sequences
There are 5 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
P30839 | AL3A2_RAT | Aldh3a2 | 484 | ||
A0A8I6GJ33 | A0A8I6GJ33_RAT | Aldh3a2 | 487 | ||
A0A8I6AE89 | A0A8I6AE89_RAT | Aldh3a2 | 519 | ||
A0A8I6AF13 | A0A8I6AF13_RAT | Aldh3a2 | 584 | ||
G3V9W6 | G3V9W6_RAT | Aldh3a2 | 561 |
Keywords
- Technical term