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A0A0G2JY43 · A0A0G2JY43_RAT

  • Protein
    Aldehyde dehydrogenase
  • Gene
    Aldh3a2
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    4/5

Function

Catalytic activity

  • (2E)-hexadecenal + NAD+ + H2O = (E)-hexadec-2-enoate + NADH + 2 H+
  • (2E,6E)-farnesal + NAD+ + H2O = (2E,6E)-farnesoate + NADH + 2 H+
    EC:1.2.1.94 (UniProtKB | ENZYME | Rhea)
  • hexadecanoate + NADH + 2 H+ = hexadecanal + NAD+ + H2O
  • 2,6,10,14-tetramethylpentadecanal + NAD+ + H2O = 2,6,10,14-tetramethylpentadecanoate + NADH + 2 H+
  • 22-oxodocosanoate + NAD+ + H2O = docosanedioate + NADH + 2 H+
  • octadecanal + NAD+ + H2O = octadecanoate + NADH + 2 H+
  • octanal + NAD+ + H2O = octanoate + NADH + 2 H+
  • tetradecanal + NAD+ + H2O = tetradecanoate + NADH + 2 H+
  • heptanal + NAD+ + H2O = heptanoate + NADH + 2 H+
  • a fatty aldehyde + NAD+ + H2O = a fatty acid + NADH + 2 H+
  • an aldehyde + NAD+ + H2O = a carboxylate + NADH + 2 H+
    EC:1.2.1.3 (UniProtKB | ENZYME | Rhea)
  • decanal + NAD+ + H2O = decanoate + NADH + 2 H+
  • dodecanoate + NADH + 2 H+ = dodecanal + NAD+ + H2O

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site207
Active site241

GO annotations

AspectTerm
Cellular Componentendoplasmic reticulum membrane
Molecular Functionoxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
Biological Processcellular aldehyde metabolic process
Biological Processfatty acid metabolic process

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Aldehyde dehydrogenase

Gene names

    • Name
      Aldh3a2

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Brown Norway
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus

Accessions

  • Primary accession
    A0A0G2JY43

Proteomes

Organism-specific databases

Subcellular Location

Endoplasmic reticulum membrane
; Single-pass membrane protein
Microsome membrane

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane464-482Helical

Keywords

Expression

Gene expression databases

Interaction

Subunit

Homodimer.

Structure

3D structure databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain3-421Aldehyde dehydrogenase

Sequence similarities

Belongs to the aldehyde dehydrogenase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    483
  • Mass (Da)
    53,938
  • Last updated
    2022-05-25 v2
  • MD5 Checksum
    8D7A8B3350564C84DFA1502D986A5092
MERQVQRLRQTFRSGRSRPLRFRLQQLEALRRMVQEREKDILAAIAADLSKSELNAYSHEVITILGEIDFMLGNLPELASARPAKKNLLTMMDEAYVQPEPLGVVLIIGAWNYPFVLTLQPLVGAIAAGNAAIVKPSELSENTAKILAELLPQYLDQDLYMIVNGGVEETTELLRQRFDHILYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDRDCDLDVACRRITWGKYMNCGQTCIAPDYILCEASLQDQIVQKIKDTVKDFYGENVKASPDYERIINLRHFKRIKSLLEGQKIAFGGETDEATRYIAPTILTDVDPNSKVMQEEIFGPILPIVSVKNVEEAINFINDREKPLALYIFSHNNKLIKRVIDETSSGGVTGNDVIMHFTVNSLPFGGVGASGMGAYHGKYSFDTFSHQRPCLLKGLKGESVNKLRYPPNSESKVSWSKFFLLKQFNKGRLQLLLLVCLVAVAAVIVKVS

Computationally mapped potential isoform sequences

There are 5 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
P30839AL3A2_RATAldh3a2484
A0A8I6GJ33A0A8I6GJ33_RATAldh3a2487
A0A8I6AE89A0A8I6AE89_RATAldh3a2519
A0A8I6AF13A0A8I6AF13_RATAldh3a2584
G3V9W6G3V9W6_RATAldh3a2561

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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