A0A0G2JSI1 · A0A0G2JSI1_RAT

  • Protein
    4-trimethylaminobutyraldehyde dehydrogenase
  • Gene
    Aldh9a1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    5/5

Function

function

Converts gamma-trimethylaminobutyraldehyde into gamma-butyrobetaine with high efficiency (in vitro). Can catalyze the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction, but with low efficiency. Catalyzes the oxidation of aldehydes arising from biogenic amines and polyamines.

Catalytic activity

Pathway

Amine and polyamine biosynthesis; carnitine biosynthesis.

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site278

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Function4-trimethylammoniobutyraldehyde dehydrogenase activity
Biological Processcarnitine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    4-trimethylaminobutyraldehyde dehydrogenase
  • EC number
  • Alternative names
    • Aldehyde dehydrogenase family 9 member A1
    • Formaldehyde dehydrogenase
    • Gamma-aminobutyraldehyde dehydrogenase

Gene names

    • Name
      Aldh9a1

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Brown Norway
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus

Accessions

  • Primary accession
    A0A0G2JSI1

Proteomes

Organism-specific databases

Subcellular Location

PTM/Processing

Proteomic databases

Expression

Gene expression databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain52-507Aldehyde dehydrogenase

Sequence similarities

Belongs to the aldehyde dehydrogenase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    521
  • Mass (Da)
    56,469
  • Last updated
    2022-05-25 v2
  • Checksum
    99604CF61A35AA12
MFLSAVGPVLTSLLRVPRPAAVAAMSTGTFVVSQPLNYRGGARVEPVDASGTEKAFEPATGREIATFKCSGEKEVNLAVENAKAAFKIWSKKSGLERCQVLLEAARIIKERRDEIAIMETINNGKSIFEARLDVDTSWQCLEYYAGLAASMAGEHIQLPGGSFGYTRREPLGVCLGIGAWNYPFQIACWKSAPALACGNAMIFKPSPFTPVSALLLAEIYTKAGAPNGLFNVVQGGAATGQFLCQHRDVAKVSFTGSVPTGMKIMEMAAKGIKPITLELGGKSPLIIFSDCNMKNAVKGALLANFLTQGQVCCNGTRVFVQKEIADAFTKEVVRQTQRIKIGDPLLEDTRMGPLINAPHLERVLGFVRSAKEQGATVLCGGEPYAPEDPKLKHGYYMTPCILTNCTDDMTCVKEEIFGPVMSILTFETEAEVLERANDTTFGLAAGVFTRDIQRAHRVAAELQAGTCYINNYNVSPVELPFGGYKKSGFGRENGRVTIEYYSQLKTVCVEMGDVESPFENQ

Computationally mapped potential isoform sequences

There are 3 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q9JLJ3AL9A1_RATAldh9a1494
A0A8I6AQJ5A0A8I6AQJ5_RATAldh9a1497
A0A8I6ASL3A0A8I6ASL3_RATAldh9a1517

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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