Lineage-specific biology revealed by a finished genome assembly of the mouse.Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L.[...], Ponting C.P.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainC57BL/6JCategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS Biol. 7:E1000112-E1000112 (2009)Cited in99+99+
Modernizing reference genome assemblies.Church D.M., Schneider V.A., Graves T., Auger K., Cunningham F., Bouk N., Chen H.C., Agarwala R., McLaren W.M.[...], Hubbard T.Cited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainC57BL/6JCategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS Biol 9:e1001091-e1001091 (2011)Cited in99+
No title available.EnsemblCited forIDENTIFICATIONStrainC57BL/6JSourceUniProtKB unreviewed (TrEMBL)Submission Submitted to UniProtKB (AUG-2024)Cited in99+
Phenotypic abnormalities in macrophages from leptin-deficient, obese mice.Lee F.Y., Li Y., Yang E.K., Yang S.Q., Lin H.Z., Trush M.A., Dannenberg A.J., Diehl A.M.View abstractCategoriesFunctionSourceMGI: 96559PubMedEurope PMCAm J Physiol 276:C386-94 (1999)Mapped to24
Activation of gp130 signaling in vivo by the IL-6 super-agonist K-7/D-6 accelerates repopulation of lymphoid organs after irradiation.Frasca D., Doria G., Barattini P., Guidi F., Salvati A.L., Toniatti C., Ciliberto G.View abstractCategoriesFunctionSourceMGI: 96559PubMedEurope PMCEur J Immunol 29:300-310 (1999)Mapped to17
Mitosis and apoptosis in the liver of interleukin-6-deficient mice after partial hepatectomy.Sakamoto T., Liu Z., Murase N., Ezure T., Yokomuro S., Poli V., Demetris A.J.View abstractCategoriesFunctionSourceMGI: 96559PubMedEurope PMCHepatology 29:403-411 (1999)Mapped to7
IL-6 deficiency leads to increased emotionality in mice: evidence in transgenic mice carrying a null mutation for IL-6.Armario A., Hernandez J., Bluethmann H., Hidalgo J.View abstractCategoriesPhenotypes & VariantsSourceMGI: 96559PubMedEurope PMCJ Neuroimmunol 92:160-169 (1998)Mapped to7
Targeted disruption of migration inhibitory factor gene reveals its critical role in sepsis.Bozza M., Satoskar A.R., Lin G., Lu B., Humbles A.A., Gerard C., David J.R.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 96559PubMedEurope PMCJ Exp Med 189:341-346 (1999)Mapped to18
Behavioural characterization of interleukin-6 overexpressing or deficient mice during agonistic encounters.Alleva E., Cirulli F., Bianchi M., Bondiolotti G.P., Chiarotti F., De Acetis L., Panerai A.E.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 96559PubMedEurope PMCEur J Neurosci 10:3664-3672 (1998)Mapped to7
IL-6-deficient mice are resistant to experimental autoimmune encephalomyelitis: roles of IL-6 in the activation and differentiation of autoreactive T cells.Samoilova E.B., Horton J.L., Hilliard B., Liu T.S., Chen Y.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 96559PubMedEurope PMCJ Immunol 161:6480-6486 (1998)Mapped to7
The combined inactivation of tumor necrosis factor and interleukin-6 prevents induction of the major acute phase proteins by endotoxin.Bopst M., Haas C., Car B., Eugster H.P.View abstractCategoriesFunction, SequencesSourceMGI: 96559PubMedEurope PMCEur J Immunol 28:4130-4137 (1998)Mapped to16
Identification of a signal transducer and activator of transcription (STAT) binding site in the mouse metallothionein-I promoter involved in interleukin-6-induced gene expression.Lee D.K., Carrasco J., Hidalgo J., Andrews G.K.View abstractCategoriesFunctionSourceMGI: 96559PubMedEurope PMCBiochem J 337:59-65 (1999)Mapped to17
CSF-1 regulation of Il6 gene expression by murine macrophages: a pivotal role for GM-CSF.Evans R., Shultz L.D., Dranoff G., Fuller J.A., Kamdar S.J.View abstractCategoriesSequencesSourceMGI: 96559PubMedEurope PMCJ Leukoc Biol 64:810-816 (1998)Mapped to10
Spinal nerve lesion-induced mechanoallodynia and adrenergic sprouting in sensory ganglia are attenuated in interleukin-6 knockout mice.Ramer M.S., Murphy P.G., Richardson P.M., Bisby M.A.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 96559PubMedEurope PMCPain 78:115-121 (1998)Mapped to7
Interleukin 6 influences germinal center development and antibody production via a contribution of C3 complement component.Kopf M., Herren S., Wiles M.V., Pepys M.B., Kosco-Vilbois M.H.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 96559PubMedEurope PMCJ Exp Med 188:1895-1906 (1998)Mapped to13
Assignment of mouse cardiac two-pore background K+ channel gene (Kcnk4) to the proximal region of mouse chromosome 5.Fujita A., Horio Y., Copeland N.G., Gilbert D.J., Jenkins N.A., Kurachi Y.CategoriesFunction, SequencesSourceMGI: 96559PubMedEurope PMCGenomics 54:183-184 (1998)Mapped to12
Borrelia burgdorferi-infected, interleukin-6-deficient mice have decreased Th2 responses and increased lyme arthritis.Anguita J., Rincon M., Samanta S., Barthold S.W., Flavell R.A., Fikrig E.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 96559PubMedEurope PMCJ Infect Dis 178:1512-1515 (1998)Mapped to17
IL-6 knock-out mice show modified basal immune functions, but normal immune responses to stress.Manfredi B., Sacerdote P., Gaspani L., Poli V., Panerai A.E.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 96559PubMedEurope PMCBrain Behav Immun 12:201-211 (1998)Mapped to7
Interleukin 6 dependence of anti-DNA antibody production: evidence for two pathways of autoantibody formation in pristane-induced lupus.Richards H.B., Satoh M., Shaw M., Libert C., Poli V., Reeves W.H.View abstractCategoriesSequencesSourceMGI: 96559PubMedEurope PMCJ Exp Med 188:985-990 (1998)Mapped to7
Hepatocellular hyperplasia, plasmacytoma formation, and extramedullary hematopoiesis in interleukin (IL)-6/soluble IL-6 receptor double-transgenic mice.Schirmacher P., Peters M., Ciliberto G., Blessing M., Lotz J., Meyer zum Buschenfelde K.H., Rose-John S.View abstractCategoriesFunctionSourceMGI: 96559PubMedEurope PMCAm J Pathol 153:639-648 (1998)Mapped to11
Elevation of IL-6 in transgenic mice results in increased levels of the 90 kDa heat shock protein (hsp90) and the production of anti-hsp90 antibodies.Stephanou A., Conroy S., Isenberg D.A., Maione D., Poli V., Ciliberto G., Latchman D.S.View abstractCategoriesSequencesSourceMGI: 96559PubMedEurope PMCJ Autoimmun 11:249-253 (1998)Mapped to18
Role of IL-6 and TNF in thermoregulation and survival during sepsis in mice.Leon L.R., White A.A., Kluger M.J.View abstractCategoriesPhenotypes & VariantsSourceMGI: 96559PubMedEurope PMCAm J Physiol 275:R269-77 (1998)Mapped to27
Interleukin-6 and tumor necrosis factor-alpha type 1 receptor deficient mice reveal a role of IL-6 and TNF-alpha on brain metallothionein-I and -III regulation.Carrasco J., Hernandez J., Bluethmann H., Hidalgo J.View abstractCategoriesExpressionSourceMGI: 96559PubMedEurope PMCBrain Res Mol Brain Res 57:221-234 (1998)Mapped to24
Regulation of interleukin-6 and interleukin-6R alpha (gp80) expression by murine immunoglobulin-secreting B-cell hybridomas.Iwasaki T., Hamano T., Fujimoto J., Kakishita E.View abstractCategoriesExpressionSourceMGI: 96559PubMedEurope PMCImmunology 93:498-504 (1998)Mapped to11
Interleukin 6 plays a key role in the development of antigen-induced arthritis.Ohshima S., Saeki Y., Mima T., Sasai M., Nishioka K., Nomura S., Kopf M., Katada Y., Tanaka T.[...], Kishimoto T.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 96559PubMedEurope PMCProc Natl Acad Sci U S A 95:8222-8226 (1998)Mapped to7
IL-6-deficient mice are resistant to the induction of experimental autoimmune encephalomyelitis provoked by myelin oligodendrocyte glycoprotein.Okuda Y., Sakoda S., Bernard C.C., Fujimura H., Saeki Y., Kishimoto T., Yanagihara T.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 96559PubMedEurope PMCInt Immunol 10:703-708 (1998)Mapped to7
Conservation of structure and function between human and murine IL-16.Keane J., Nicoll J., Kim S., Wu D.M.H., Cruikshank W.W., Brazer W., Natke B., Zhang Y., Center D.M., Kornfeld H.View abstractCategoriesSequencesSourceMGI: 96559PubMedEurope PMCJ. Immunol. 160:5945-5954 (1998)Cited in1Mapped to10
Chromosomal localization of mouse Cenpa gene.Fowler K.J., Newson A.J., MacDonald A.C., Kalitsis P., Lyu M.S., Kozak C.A., Choo K.H.View abstractCategoriesSequencesSourceMGI: 96559PubMedEurope PMCCytogenet Cell Genet 79:298-301 (1997)Mapped to38
Testosterone and IL-6 requirements for human C-reactive protein gene expression in transgenic mice.Szalai A.J., van Ginkel F.W., Dalrymple S.A., Murray R., McGhee J.R., Volanakis J.E.View abstractCategoriesFunction, ExpressionSourceMGI: 96559PubMedEurope PMCJ Immunol 160:5294-5299 (1998)Mapped to7
Interleukin-6 functions in autoimmune encephalomyelitis: a study in gene- targeted mice.Mendel I., Katz A., Kozak N., Ben-Nun A., Revel M.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 96559PubMedEurope PMCEur J Immunol 28:1727-1737 (1998)Mapped to7
Lipopolysaccharide (LPS)-induced IL-6 production by embryonic fibroblasts isolated and cloned from LPS-responsive and LPS-hyporesponsive mice.Tominaga K., Kirikae T., Nakano M.View abstractCategoriesSequencesSourceMGI: 96559PubMedEurope PMCMol Immunol 34:1147-1156 (1997)Mapped to7
The use of knockout mice to understand the role of cytokines in fever.Kluger M.J., Kozak W., Leon L.R., Conn C.A.View abstractCategoriesFunctionSourceMGI: 96559PubMedEurope PMCClin Exp Pharmacol Physiol 25:141-144 (1998)Mapped to9
Structure of the TCR expressed on a gastritogenic T cell clone, II-6, and frequent appearance of similar clonotypes in mice bearing autoimmune gastritis.Katakai T., Agata Y., Shimizu A., Ohshima C., Nishio A., Inaba M., Kasakura S., Mori K.J., Masuda T.View abstractCategoriesSequencesSourceMGI: 96559PubMedEurope PMCInt Immunol 9:1849-1855 (1997)Mapped to10
Interleukin 6 is required for the development of collagen-induced arthritis.Alonzi T., Fattori E., Lazzaro D., Costa P., Probert L., Kollias G., De Benedetti F., Poli V., Ciliberto G.View abstractCategoriesPhenotypes & VariantsSourceMGI: 96559PubMedEurope PMCJ Exp Med 187:461-468 (1998)Mapped to7
Oncostatin M stimulates excessive extracellular matrix accumulation in a transgenic mouse model of connective tissue disease.Bamber B., Reife R.A., Haugen H.S., Clegg C.H.View abstractCategoriesFunction, ExpressionSourceMGI: 96559PubMedEurope PMCJ Mol Med (Berl) 76:61-69 (1998)Mapped to7
IL-6 is an antiinflammatory cytokine required for controlling local or systemic acute inflammatory responses.Xing Z., Gauldie J., Cox G., Baumann H., Jordana M., Lei X.F., Achong M.K.View abstractCategoriesFunctionSourceMGI: 96559PubMedEurope PMCJ Clin Invest 101:311-320 (1998)Mapped to7
Interleukin-6 does not mediate endotoxin-induced uveitis in mice: studies in gene deletion animals.Rosenbaum J.T., Kievit P., Han Y.B., Park J.M., Planck S.R.View abstractCategoriesSequencesSourceMGI: 96559PubMedEurope PMCInvest Ophthalmol Vis Sci 39:64-69 (1998)Mapped to7
Nociceptive responses in interleukin-6-deficient mice to peripheral inflammation and peripheral nerve section.Xu X.J., Hao J.X., Andell-Jonsson S., Poli V., Bartfai T., Wiesenfeld-Hallin Z.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 96559PubMedEurope PMCCytokine 9:1028-1033 (1997)Mapped to7
Mapping of eight testis-specific genes to mouse chromosomes.Taketo M.M., Araki Y., Matsunaga A., Yokoi A., Tsuchida J., Nishina Y., Nozaki M., Tanaka H., Koga M.[...], Seldin M.F.View abstractCategoriesSequencesSourceMGI: 96559PubMedEurope PMCGenomics 46:138-142 (1997)Mapped to99+
Transgenic expression of interleukin 6 in the central nervous system regulates brain metallothionein-I and -III expression in mice.Hernandez J., Molinero A., Campbell I.L., Hidalgo J.View abstractCategoriesSequences, ExpressionSourceMGI: 96559PubMedEurope PMCBrain Res Mol Brain Res 48:125-131 (1997)Mapped to15
Interleukin-6-dependent and -independent regulation of the human C- reactive protein gene.Weinhold B., Ruther U.View abstractCategoriesSequencesSourceMGI: 96559PubMedEurope PMCBiochem J 327:425-429 (1997)Mapped to7
Lethal tuberculosis in interleukin-6-deficient mutant mice.Ladel C.H., Blum C., Dreher A., Reifenberg K., Kopf M., Kaufmann S.H.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 96559PubMedEurope PMCInfect Immun 65:4843-4849 (1997)Mapped to7
Two isoforms of the mouse ether-a-go-go-related gene coassemble to form channels with properties similar to the rapidly activating component of the cardiac delayed rectifier K+ current.London B., Trudeau M.C., Newton K.P., Beyer A.K., Copeland N.G., Gilbert D.J., Jenkins N.A., Satler C.A., Robertson G.A.View abstractCategoriesSequencesSourceMGI: 96559PubMedEurope PMCCirc. Res. 81:870-878 (1997)Cited in2Mapped to15
Semi-quantitative polymerase chain reaction analysis of cytokine and cytokine receptor gene expression during thymic ontogeny.Montgomery R.A., Dallman M.J.View abstractCategoriesSequencesSourceMGI: 96559PubMedEurope PMCCytokine 9:717-726 (1997)Mapped to69
Altered expression of interleukin 6 and interleukin 10 as a result of photodynamic therapy in vivo.Gollnick S.O., Liu X., Owczarczak B., Musser D.A., Henderson B.W.View abstractCategoriesSequencesSourceMGI: 96559PubMedEurope PMCCancer Res 57:3904-3909 (1997)Mapped to10
Defective development of pristane-oil-induced plasmacytomas in interleukin-6-deficient BALB/c mice.Lattanzio G., Libert C., Aquilina M., Cappelletti M., Ciliberto G., Musiani P., Poli V.View abstractCategoriesSequences, Phenotypes & VariantsSourceMGI: 96559PubMedEurope PMCAm J Pathol 151:689-696 (1997)Mapped to7
Role of interleukin-6 in the pathogenesis of murine plasmacytoma and human multiple myeloma.Pattengale P.K.CategoriesFunction, SequencesSourceMGI: 96559PubMedEurope PMCAm J Pathol 151:647-649 (1997)Mapped to7
Priming of mouse macrophages with the macrophage colony-stimulating factor (CSF-1) induces a variety of pathways that regulate expression of the interleukin 6 (Il6) and granulocyte-macrophage colony-stimulating factor (Csfgm) genes.Kamdar S.J., Fuller J.A., Nishikawa S.I., Evans R.View abstractCategoriesSequencesSourceMGI: 96559PubMedEurope PMCExp Cell Res 235:108-116 (1997)Mapped to17
Regulation of tissue inhibitor of metalloproteinase-1 in fibroblasts and acute phase proteins in hepatocytes in vitro by mouse oncostatin M, cardiotrophin-1, and IL-6.Richards C.D., Kerr C., Tanaka M., Hara T., Miyajima A., Pennica D., Botelho F., Langdon C.M.View abstractCategoriesSequencesSourceMGI: 96559PubMedEurope PMCJ Immunol 159:2431-2437 (1997)Mapped to13
Interleukin-6 secretion in mice is associated with reduced glucose-6- phosphatase and liver glycogen levels.Metzger S., Goldschmidt N., Barash V., Peretz T., Drize O., Shilyansky J., Shiloni E., Chajek-Shaul T.View abstractCategoriesFunctionSourceMGI: 96559PubMedEurope PMCAm J Physiol 273:E262-7 (1997)Mapped to7