A0A0G2JE71 · A0A0G2JE71_MOUSE
- ProteinKRIT1, ankyrin repeat containing
- GeneKrit1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids132 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score1/5
Publications for A0A0G2JE71
Role of pericytes in the development of cerebral cavernous malformations.
- CategoriesFunction
- SourceMGI: 1930618
beta1 integrin monoclonal antibody treatment ameliorates cerebral cavernous malformations.
- CategoriesFunction
- SourceMGI: 1930618
Pdcd10-Stk24/25 complex controls kidney water reabsorption by regulating Aqp2 membrane targeting.
- CategoriesInteraction
- SourceMGI: 1930618
Cerebral cavernous malformations are driven by ADAMTS5 proteolysis of versican.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 1930618
Targeting miR-27a/VE-cadherin interactions rescues cerebral cavernous malformations in mice.
- CategoriesInteraction
- SourceMGI: 1930618
Distinct cellular roles for PDCD10 define a gut-brain axis in cerebral cavernous malformation.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 1930618
KRIT1 Deficiency Promotes Aortic Endothelial Dysfunction.
- CategoriesFunction
- SourceMGI: 1930618
Cerebral cavernous malformations form an anticoagulant vascular domain in humans and mice.
- CategoriesFunction, Expression
- SourceMGI: 1930618
Thrombospondin1 (TSP1) replacement prevents cerebral cavernous malformations.
- CategoriesFunction
- SourceMGI: 1930618
Up-regulation of NADPH oxidase-mediated redox signaling contributes to the loss of barrier function in KRIT1 deficient endothelium.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 1930618
Endothelial TLR4 and the microbiome drive cerebral cavernous malformations.
- CategoriesFunction
- SourceMGI: 1930618
High-throughput discovery of novel developmental phenotypes.
- CategoriesSequences, Phenotypes & Variants
- SourceMGI: 1930618
Micro-CT Imaging Reveals Mekk3 Heterozygosity Prevents Cerebral Cavernous Malformations in Ccm2-Deficient Mice.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 1930618
Phosphoinositide 3-Kinase (PI3K) Subunit p110delta Is Essential for Trophoblast Cell Differentiation and Placental Development in Mouse.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 1930618
Cerebral cavernous malformations arise from endothelial gain of MEKK3- KLF2/4 signalling.
- CategoriesInteraction
- SourceMGI: 1930618
KLF4 is a key determinant in the development and progression of cerebral cavernous malformations.
- CategoriesFunction
- SourceMGI: 1930618
Endothelial Erg expression is required for embryogenesis and vascular integrity.
- CategoriesFunction, Expression
- SourceMGI: 1930618
Lack of CCM1 induces hypersprouting and impairs response to flow.
- CategoriesFunction
- SourceMGI: 1930618
KRIT1 loss of function causes a ROS-dependent upregulation of c-Jun.
- CategoriesFunction
- SourceMGI: 1930618
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 1930618