Lineage-specific biology revealed by a finished genome assembly of the mouse.Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L.[...], Ponting C.P.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainC57BL/6JCategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS Biol. 7:E1000112-E1000112 (2009)Cited in99+99+
Modernizing reference genome assemblies.Church D.M., Schneider V.A., Graves T., Auger K., Cunningham F., Bouk N., Chen H.C., Agarwala R., McLaren W.M.[...], Hubbard T.Cited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainC57BL/6JCategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS Biol 9:e1001091-e1001091 (2011)Cited in99+
No title available.EnsemblCited forIDENTIFICATIONStrainC57BL/6JSourceUniProtKB unreviewed (TrEMBL)Submission Submitted to UniProtKB (JUN-2024)Cited in99+
Genetic determinants of micronucleus formation in vivo.Adams D.J., Barlas B., McIntyre R.E., Salguero I., van der Weyden L., Barros A., Vicente J.R., Karimpour N., Haider A.[...], White J.K.View abstractSourceMGI: 1930618PubMedEurope PMCNature 627:130-136 (2024)Mapped to99+
Role of pericytes in the development of cerebral cavernous malformations.Dai Z., Li J., Li Y., Wang R., Yan H., Xiong Z., Wu S., Yang X., Lu D.[...], Shi C.View abstractCategoriesFunctionSourceMGI: 1930618PubMedEurope PMCiScience 25:105642-105642 (2022)Mapped to5
beta1 integrin monoclonal antibody treatment ameliorates cerebral cavernous malformations.McCurdy S., Lin J., Shenkar R., Moore T., Lightle R., Faurobert E., Lopez-Ramirez M.A., Awad I., Ginsberg M.H.View abstractCategoriesFunctionSourceMGI: 1930618PubMedEurope PMCFASEB J 36:e22629-e22629 (2022)Mapped to5
Circulating Plasma miRNA Homologs in Mice and Humans Reflect Familial Cerebral Cavernous Malformation Disease.Romanos S.G., Srinath A., Li Y., Xie B., Chen C., Li Y., Moore T., Bi D., Sone J.Y.[...], Awad I.A.View abstractSourceMGI: 1930618PubMedEurope PMCTransl Stroke Res 14:513-529 (2023)Mapped to9
Pdcd10-Stk24/25 complex controls kidney water reabsorption by regulating Aqp2 membrane targeting.Wang R., Wu S.T., Yang X., Qian Y., Choi J.P., Gao R., Song S., Wang Y., Zhuang T.[...], Zheng X.View abstractCategoriesInteractionSourceMGI: 1930618PubMedEurope PMCJCI Insight 6:142838-142838 (2021)Mapped to25
Cerebral cavernous malformations are driven by ADAMTS5 proteolysis of versican.Hong C.C., Tang A.T., Detter M.R., Choi J.P., Wang R., Yang X., Guerrero A.A., Wittig C.F., Hobson N.[...], Kahn M.L.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1930618PubMedEurope PMCJ Exp Med 217:e20200140-e20200140 (2020)Mapped to60
Targeting miR-27a/VE-cadherin interactions rescues cerebral cavernous malformations in mice.Li J., Zhao Y., Choi J., Ting K.K., Coleman P., Chen J., Cogger V.C., Wan L., Shi Z.[...], Gamble J.R.View abstractCategoriesInteractionSourceMGI: 1930618PubMedEurope PMCPLoS Biol 18:e3000734-e3000734 (2020)Mapped to14
Distinct cellular roles for PDCD10 define a gut-brain axis in cerebral cavernous malformation.Tang A.T., Sullivan K.R., Hong C.C., Goddard L.M., Mahadevan A., Ren A., Pardo H., Peiper A., Griffin E.[...], Kahn M.L.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1930618PubMedEurope PMCSci Transl Med 11:eaaw3521-eaaw3521 (2019)Mapped to32
KRIT1 Deficiency Promotes Aortic Endothelial Dysfunction.Vieceli Dalla Sega F., Mastrocola R., Aquila G., Fortini F., Fornelli C., Zotta A., Cento A.S., Perrelli A., Boda E.[...], Retta S.F.View abstractCategoriesFunctionSourceMGI: 1930618PubMedEurope PMCInt J Mol Sci 20:E4930-E4930 (2019)Mapped to5
Comprehensive transcriptome analysis of cerebral cavernous malformation across multiple species and genotypes.Koskimaki J., Girard R., Li Y., Saadat L., Zeineddine H.A., Lightle R., Moore T., Lyne S., Avner K.[...], Awad I.A.View abstractCategoriesExpressionSourceMGI: 1930618PubMedEurope PMCJCI Insight 4:e126167-e126167 (2019)Mapped to9
Cerebral cavernous malformations form an anticoagulant vascular domain in humans and mice.Lopez-Ramirez M.A., Pham A., Girard R., Wyseure T., Hale P., Yamashita A., Koskimaki J., Polster S., Saadat L.[...], Ginsberg M.H.View abstractCategoriesFunction, ExpressionSourceMGI: 1930618PubMedEurope PMCBlood 133:193-204 (2019)Mapped to11
Thrombospondin1 (TSP1) replacement prevents cerebral cavernous malformations.Lopez-Ramirez M.A., Fonseca G., Zeineddine H.A., Girard R., Moore T., Pham A., Cao Y., Shenkar R., de Kreuk B.J.[...], Ginsberg M.H.View abstractCategoriesFunctionSourceMGI: 1930618PubMedEurope PMCJ Exp Med 214:3331-3346 (2017)Mapped to11
Up-regulation of NADPH oxidase-mediated redox signaling contributes to the loss of barrier function in KRIT1 deficient endothelium.Goitre L., DiStefano P.V., Moglia A., Nobiletti N., Baldini E., Trabalzini L., Keubel J., Trapani E., Shuvaev V.V.[...], Glading A.J.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1930618PubMedEurope PMCSci Rep 7:8296-8296 (2017)Mapped to5
Endothelial TLR4 and the microbiome drive cerebral cavernous malformations.Tang A.T., Choi J.P., Kotzin J.J., Yang Y., Hong C.C., Hobson N., Girard R., Zeineddine H.A., Lightle R.[...], Kahn M.L.View abstractCategoriesFunctionSourceMGI: 1930618PubMedEurope PMCNature 545:305-310 (2017)Mapped to23
High-throughput discovery of novel developmental phenotypes.International Mouse Phenotyping ConsortiumDickinson M.E., Flenniken A.M., Ji X., Teboul L., Wong M.D., White J.K., Meehan T.F., Weninger W.J., Westerberg H.[...], Murakami A.View abstractCategoriesSequences, Phenotypes & VariantsSourceMGI: 1930618PubMedEurope PMCNature 537:508-514 (2016)Mapped to99+
Micro-CT Imaging Reveals Mekk3 Heterozygosity Prevents Cerebral Cavernous Malformations in Ccm2-Deficient Mice.Choi J.P., Foley M., Zhou Z., Wong W.Y., Gokoolparsadh N., Arthur J.S., Li D.Y., Zheng X.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1930618PubMedEurope PMCPLoS One 11:e0160833-e0160833 (2016)Mapped to14
Phosphoinositide 3-Kinase (PI3K) Subunit p110delta Is Essential for Trophoblast Cell Differentiation and Placental Development in Mouse.Hu X., Li J., Zhang Q., Zheng L., Wang G., Zhang X., Zhang J., Gu Q., Ye Y.[...], Wang L.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1930618PubMedEurope PMCSci Rep 6:28201-28201 (2016)Mapped to99+
Cerebral cavernous malformations arise from endothelial gain of MEKK3- KLF2/4 signalling.Zhou Z., Tang A.T., Wong W.Y., Bamezai S., Goddard L.M., Shenkar R., Zhou S., Yang J., Wright A.C.[...], Kahn M.L.View abstractCategoriesInteractionSourceMGI: 1930618PubMedEurope PMCNature 532:122-126 (2016)Mapped to28
KLF4 is a key determinant in the development and progression of cerebral cavernous malformations.Cuttano R., Rudini N., Bravi L., Corada M., Giampietro C., Papa E., Morini M.F., Maddaluno L., Baeyens N.[...], Dejana E.View abstractCategoriesFunctionSourceMGI: 1930618PubMedEurope PMCEMBO Mol Med 8:6-24 (2016)Mapped to18
Endothelial Erg expression is required for embryogenesis and vascular integrity.Han R., Pacifici M., Iwamoto M., Trojanowska M.View abstractCategoriesFunction, ExpressionSourceMGI: 1930618PubMedEurope PMCOrganogenesis 11:75-86 (2015)Mapped to29
The cerebral cavernous malformation pathway controls cardiac development via regulation of endocardial MEKK3 signaling and KLF expression.Zhou Z., Rawnsley D.R., Goddard L.M., Pan W., Cao X.J., Jakus Z., Zheng H., Yang J., Arthur J.S.[...], Kahn M.L.View abstractCategoriesFunctionSourceMGI: 1930618PubMedEurope PMCDev Cell 32:168-180 (2015)Mapped to33
KRIT1 protein depletion modifies endothelial cell behavior via increased vascular endothelial growth factor (VEGF) signaling.DiStefano P.V., Kuebel J.M., Sarelius I.H., Glading A.J.View abstractCategoriesInteractionSourceMGI: 1930618PubMedEurope PMCJ Biol Chem 289:33054-33065 (2014)Mapped to26