A0A0F9YU98 · A0A0F9YU98_9BACT
- ProteinMultifunctional fusion protein
- GenemurI
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids669 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
function
Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
Provides the (R)-glutamate required for cell wall biosynthesis.
Catalytic activity
- ATP + D-glutamate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine = ADP + H+ + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate
Pathway
Cell wall biogenesis; peptidoglycan biosynthesis.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 7-8 | substrate | ||||
Sequence: DS | ||||||
Binding site | 39-40 | substrate | ||||
Sequence: YG | ||||||
Active site | 70 | Proton donor/acceptor | ||||
Sequence: C | ||||||
Binding site | 71-72 | substrate | ||||
Sequence: NT | ||||||
Active site | 185 | Proton donor/acceptor | ||||
Sequence: C | ||||||
Binding site | 186-187 | substrate | ||||
Sequence: TH | ||||||
Binding site | 363-369 | ATP (UniProtKB | ChEBI) | ||||
Sequence: GSKGKST |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | glutamate racemase activity | |
Molecular Function | UDP-N-acetylmuramoylalanine-D-glutamate ligase activity | |
Biological Process | cell division | |
Biological Process | cell wall organization | |
Biological Process | peptidoglycan biosynthetic process | |
Biological Process | regulation of cell shape |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMultifunctional fusion protein
Including 2 domains:
- Recommended nameUDP-N-acetylmuramoylalanine--D-glutamate ligase
- EC number
- Alternative names
- Recommended nameGlutamate racemase
- EC number
Gene names
Organism names
- Taxonomic lineageBacteria
Accessions
- Primary accessionA0A0F9YU98
Proteomes
Subcellular Location
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 361-498 | Mur ligase central | ||||
Sequence: ITGSKGKSTTTALIYKVLKSKLKEKVLLAGNLVLNKSPLNFLSKVKKNSVIILELSSWDLRNLGEYKISPNIAVVTNIIPDHLNKYKNIKEYEKDKKNIFEYQGKHDILFLNKNDKKLLKWQNQVKSKVEFFNGTNKD | ||||||
Domain | 526-643 | Mur ligase C-terminal | ||||
Sequence: HRQEFVKELRGVKFYNDSAATIPEATIKAIDDLKPKFGNLILILGGVDKNLEYKKLANKIIRNKDSVKAILLPGTASNKIIENFKKMKHIFTKVENLKQAVNEALKVSKKDDIIILSP |
Sequence similarities
Belongs to the MurCDEF family.
Belongs to the aspartate/glutamate racemases family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length669
- Mass (Da)76,152
- Last updated2015-07-22 v1
- Checksum34B43057FB57594C
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
LBOD01000006 EMBL· GenBank· DDBJ | KKP30051.1 EMBL· GenBank· DDBJ | Genomic DNA |