A0A0F8L8Q5 · A0A0F8L8Q5_METMZ
- ProteinDNA-directed RNA polymerase subunit Rpo3
- Generpo3
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids266 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Catalytic activity
- RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate
Cofactor
Note: Binds 1 [3Fe-4S] cluster.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 205 | [3Fe-4S] cluster (UniProtKB | ChEBI) | |||
Binding site | 208 | [3Fe-4S] cluster (UniProtKB | ChEBI) | |||
Binding site | 211 | [3Fe-4S] cluster (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | DNA-directed RNA polymerase complex | |
Molecular Function | 3 iron, 4 sulfur cluster binding | |
Molecular Function | DNA binding | |
Molecular Function | DNA-directed 5'-3' RNA polymerase activity | |
Molecular Function | metal ion binding | |
Molecular Function | protein dimerization activity | |
Biological Process | DNA-templated transcription |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDNA-directed RNA polymerase subunit Rpo3
- EC number
- Alternative names
Gene names
Organism names
- Strains
- Taxonomic lineageArchaea > Euryarchaeota > Stenosarchaea group > Methanomicrobia > Methanosarcinales > Methanosarcinaceae > Methanosarcina
Accessions
- Primary accessionA0A0F8L8Q5
Proteomes
Subcellular Location
Interaction
Subunit
Part of the RNA polymerase complex.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 164-193 | 4Fe-4S ferredoxin-type | |||
Domain | 195-225 | 4Fe-4S ferredoxin-type | |||
Sequence similarities
Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length266
- Mass (Da)28,924
- Last updated2015-07-22 v1
- MD5 Checksum3D9F07A4DEE97C0292B1ED543D459B3D
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JJPI01000124 EMBL· GenBank· DDBJ | KKG51336.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JJPK01000065 EMBL· GenBank· DDBJ | KKG61353.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JJPJ01000044 EMBL· GenBank· DDBJ | KKG64005.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JJPU01000203 EMBL· GenBank· DDBJ | KKG91476.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JJPV01000126 EMBL· GenBank· DDBJ | KKG96423.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JJPW01000013 EMBL· GenBank· DDBJ | KKH03509.1 EMBL· GenBank· DDBJ | Genomic DNA |