A0A0F8AZ51 · A0A0F8AZ51_LARCR
- Protein5-hydroxytryptamine receptor 3A
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids368 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons.
Catalytic activity
- Ca2+(in) = Ca2+(out)
- K+(in) = K+(out)
- Na+(in) = Na+(out)
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | neuron projection | |
Cellular Component | postsynaptic membrane | |
Molecular Function | acetylcholine-gated monoatomic cation-selective channel activity | |
Molecular Function | serotonin-gated monoatomic cation channel activity |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Eupercaria > Sciaenidae > Larimichthys
Accessions
- Primary accessionA0A0F8AZ51
Subcellular Location
UniProt Annotation
GO Annotation
Postsynaptic cell membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 169-192 | Helical | |||
Transmembrane | 204-221 | Helical | |||
Transmembrane | 233-253 | Helical | |||
Transmembrane | 265-283 | Helical | |||
Transmembrane | 340-362 | Helical | |||
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 4-168 | Neurotransmitter-gated ion-channel ligand-binding | |||
Domain | 175-288 | Neurotransmitter-gated ion-channel transmembrane | |||
Sequence similarities
Belongs to the ligand-gated ion channel (TC 1.A.9) family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length368
- Mass (Da)41,891
- Last updated2015-07-22 v1
- MD5 ChecksumEFA025039B2E866C3FC42AF745E0974B
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
KQ042238 EMBL· GenBank· DDBJ | KKF17258.1 EMBL· GenBank· DDBJ | Genomic DNA |