A0A0F4ZKJ8 · A0A0F4ZKJ8_9PEZI
- ProteinCTP synthase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids583 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.
Catalytic activity
- UTP + L-glutamine + ATP + H2O = CTP + L-glutamate + ADP + phosphate + 2 H+
Pathway
Pyrimidine metabolism; CTP biosynthesis via de novo pathway; CTP from UDP: step 2/2.
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 403 | Nucleophile | |||
Active site | 532 | ||||
Active site | 534 | ||||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoophidium | |
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | CTP synthase activity | |
Molecular Function | identical protein binding | |
Biological Process | 'de novo' CTP biosynthetic process | |
Biological Process | glutamine metabolic process | |
Biological Process | pyrimidine nucleobase biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCTP synthase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Sordariomycetes > Hypocreomycetidae > Microascales > Ceratocystidaceae > Thielaviopsis
Accessions
- Primary accessionA0A0F4ZKJ8
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 2-270 | CTP synthase N-terminal | |||
Domain | 314-544 | Glutamine amidotransferase | |||
Sequence similarities
Belongs to the CTP synthase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length583
- Mass (Da)64,517
- Last updated2015-06-24 v1
- MD5 Checksum96549C9278B744D424A9F2BE48514FC9
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
LAEV01000406 EMBL· GenBank· DDBJ | KKA30388.1 EMBL· GenBank· DDBJ | Genomic DNA |