A0A0F4EQX2 · A0A0F4EQX2_9MYCO

Function

function

Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Features

Showing features for active site.

131620406080100120140160180200220240260280300
TypeIDPosition(s)Description
Active site162
Active site186
Active site261
Active site264
Active site287
Active site296O-(3'-phospho-DNA)-tyrosine intermediate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionDNA binding
Molecular Functiontyrosine-based site-specific recombinase activity
Biological Processcell division
Biological Processchromosome segregation
Biological ProcessDNA transposition

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Tyrosine recombinase XerD

Gene names

    • Name
      xerD
    • ORF names
      MLPM_1365

Organism names

  • Taxonomic identifier
  • Strain
    • Mx1-22A
  • Taxonomic lineage
    Bacteria > Bacillati > Actinomycetota > Actinomycetes > Mycobacteriales > Mycobacteriaceae > Mycobacterium

Accessions

  • Primary accession
    A0A0F4EQX2

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain4-97Core-binding (CB)
Domain118-309Tyr recombinase

Sequence similarities

Belongs to the 'phage' integrase family. XerD subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    316
  • Mass (Da)
    33,949
  • Last updated
    2015-06-24 v1
  • MD5 Checksum
    06D2EE8DAB8A31AB32EFAB9B8647BF8E
MTTAALQAQLQGYLDHLTIERSVAANTLSSYRRDLIRYSKHLLNRGIEDLAKVGEDDVSEFLVALRRGDPDSGVAALSAVSAARALIAVRGLHRFAVAEGLAELDVARTVRPPTPSRRLPKSLTVGEVLALLESVGGESPANGPLVLRNRALLELLYSTGSRISEAVGLDVDDVDTQARTVLLQGKGGKQRLVPVGRPAVQALDAYLVRGRSDLARRGPGMFMTPAIFLNARGGRLSRQSAWQVLQDAAEHAGITSGVSPHILRHSFATHLLEGGADVRVVQELLGHASVTTTQIYTLVTVHALREVWAEAHPRAK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JRPY01000056
EMBL· GenBank· DDBJ
KJX75169.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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