A0A0F2LPV0 · A0A0F2LPV0_9CREN
- ProteinTranslation initiation factor 2 subunit gamma
- Geneeif2g
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids415 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
Catalytic activity
- GTP + H2O = GDP + phosphate + H+
Cofactor
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 19 | Mg2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 19-24 | GTP (UniProtKB | ChEBI) | ||||
Sequence: DHGKTT | ||||||
Binding site | 23 | Mg2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: T | ||||||
Binding site | 44 | Mg2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: G | ||||||
Binding site | 46 | Mg2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: T | ||||||
Binding site | 59 | Zn2+ (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 62 | Zn2+ (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 74 | Zn2+ (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 77 | Zn2+ (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 149-152 | GTP (UniProtKB | ChEBI) | ||||
Sequence: NKID | ||||||
Binding site | 184-186 | GTP (UniProtKB | ChEBI) | ||||
Sequence: SAL |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | GTP binding | |
Molecular Function | GTPase activity | |
Molecular Function | metal ion binding | |
Molecular Function | translation elongation factor activity | |
Molecular Function | translation initiation factor activity | |
Molecular Function | tRNA binding | |
Biological Process | formation of translation preinitiation complex |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameTranslation initiation factor 2 subunit gamma
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageArchaea > Thermoproteota > Thermoprotei > Sulfolobales > Sulfolobaceae > Candidatus Aramenus
Accessions
- Primary accessionA0A0F2LPV0
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Subunit
Heterotrimer composed of an alpha, a beta and a gamma chain.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 7-206 | Tr-type G | ||||
Sequence: QPDVNIGVVGHVDHGKTTLVQALTGIWTSKHSEELKRGMTIKLGYAEASFGRCKSCKEPDAYVNEESCRQCGSDEEPEFIRRVSFLDAPGHEVLMATMLSGTAILDGAILVVAANEPFPQPQTREHFYALGIIGVKNLIIVQNKIDVITKEQAIEQYRQIREFVKGTWAENAPVVPVSALHKVNIDALIQTILNYIKPPQ |
Sequence similarities
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
Family and domain databases
Sequence
- Sequence statusComplete
- Length415
- Mass (Da)45,566
- Last updated2015-06-24 v1
- ChecksumC5761B5CC05E8BC9
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JZWS01000003 EMBL· GenBank· DDBJ | KJR79583.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JZWS02000001 EMBL· GenBank· DDBJ | MCL7343465.1 EMBL· GenBank· DDBJ | Genomic DNA |