A0A0F0HTX7 · A0A0F0HTX7_9PSEU
- ProteinN-acetyl-gamma-glutamyl-phosphate reductase
- GeneargC
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids359 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
Catalytic activity
- N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate = H+ + N-acetyl-L-glutamyl 5-phosphate + NADPH
Pathway
Amino-acid biosynthesis; L-arginine biosynthesis; N2-acetyl-L-ornithine from L-glutamate: step 3/4.
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 149 | |||||
Sequence: C |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | N-acetyl-gamma-glutamyl-phosphate reductase activity | |
Molecular Function | NAD binding | |
Molecular Function | NADP+ binding | |
Biological Process | arginine biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameN-acetyl-gamma-glutamyl-phosphate reductase
- EC number
- Short namesAGPR
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Pseudonocardiales > Pseudonocardiaceae > Saccharothrix
Accessions
- Primary accessionA0A0F0HTX7
Proteomes
Subcellular Location
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 4-141 | Semialdehyde dehydrogenase NAD-binding | ||||
Sequence: HIGIVGGTGHAGGELCRLLLNHPAVDTIVPTARNGEELERVHPNLLGSGLRFVTVEQLQERADELDVVFFCTPSGEAMRSAPFFLERGVKVVDVSADFRFGDPERYAAVYGEPHASPQLLPEAVYGITELHREQVATA |
Sequence similarities
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length359
- Mass (Da)38,464
- Last updated2015-06-24 v1
- ChecksumA803453B6CCD762C
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AB863705 EMBL· GenBank· DDBJ | BAR64196.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JYJF01000012 EMBL· GenBank· DDBJ | KJK58930.1 EMBL· GenBank· DDBJ | Genomic DNA |