A0A0E9NMF1 · A0A0E9NMF1_SAICN

Function

function

Catalyzes the second two steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylmonomethylethanolamine (PMME) to phosphatidyldimethylethanolamine (PDME) and of PDME to phosphatidylcholine (PC).

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Lipid metabolism.
Phospholipid metabolism; phosphatidylcholine biosynthesis.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site114-116S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site196-197S-adenosyl-L-methionine (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentendoplasmic reticulum membrane
Cellular Componentmitochondrial membrane
Molecular Functionphosphatidyl-N-dimethylethanolamine N-methyltransferase activity
Molecular Functionphosphatidyl-N-methylethanolamine N-methyltransferase activity
Biological Processmethylation
Biological Processphosphatidylcholine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphatidyl-N-methylethanolamine N-methyltransferase
  • EC number
  • Alternative names
    • Phospholipid methyltransferase
      (PLMT
      )

Gene names

    • ORF names
      G7K_5089-t1

Organism names

Accessions

  • Primary accession
    A0A0E9NMF1

Proteomes

Subcellular Location

Endoplasmic reticulum membrane
; Multi-pass membrane protein
Mitochondrion membrane
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein

Features

Showing features for topological domain, intramembrane, transmembrane.

TypeIDPosition(s)Description
Topological domain1-26Lumenal
Intramembrane27-47Helical
Transmembrane29-46Helical
Topological domain48-59Lumenal
Transmembrane66-85Helical
Transmembrane108-135Helical
Topological domain131-173Lumenal
Transmembrane172-195Helical
Topological domain195-407Cytoplasmic
Transmembrane207-225Helical
Transmembrane245-265Helical

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region388-407Disordered

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    407
  • Mass (Da)
    45,270
  • Last updated
    2015-06-24 v1
  • Checksum
    FB041E3E1E1235D2
MADLDKYLLLTKFYAQDAFSSIDWSQPSLYISVASILFNPIWWNVVARMEYHNKTLTKLAGGNAKYGCYGLAVAIFSLGIIRDFLYERALNAQPLYAPLAAYPYTKPLAVALFLTGNILVLTSMYALGVTGTYLGDYFGILMDARVTGFPFNVTDNPMYWGSAMSFLGTALWYGRPAGVVLSVVVVVMYKIALAFEEPFTGWCEGPVSFLPLGSIVGALLLQSTWRTDVAASSGVAGERRNSTFCLLWIIIFGSFTGSSGVIHLFNKGSSCFFDTIPNIRKEIYDTCIATHFITSQTTHSMMNENDRISGTAQVTKLHVKVQSMAGSVRTPWPSNSKERAGRGLWMKLWRHHFRKLGELKKKKNQRKRDMSANPSFNLVSMKHTPYLALNTPHPHAPCPSTQNKDSP

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BACD03000039
EMBL· GenBank· DDBJ
GAO50973.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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