A0A0E3ZX86 · A0A0E3ZX86_9BACT
- ProteinGlutathione hydrolase proenzyme
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids565 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- an S-substituted glutathione + H2O = an S-substituted L-cysteinylglycine + L-glutamate
Pathway
Sulfur metabolism; glutathione metabolism.
Features
Showing features for active site, binding site.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | glutathione hydrolase activity | |
Molecular Function | leukotriene C4 gamma-glutamyl transferase activity | |
Biological Process | glutathione biosynthetic process | |
Biological Process | glutathione catabolic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlutathione hydrolase proenzyme
- EC number
- Cleaved into 2 chains
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacteroidota > Cytophagia > Cytophagales > Cytophagaceae > Spirosoma
Accessions
- Primary accessionA0A0E3ZX86
Proteomes
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-20 | |||||
Sequence: MNKTILTLSCWIALFPLANA | ||||||
Chain | PRO_5002416954 | 21-565 | Glutathione hydrolase proenzyme | |||
Sequence: QDRLSGKSFATRAVVMARHGMACTSHPLSTQAAIDVLRSGGNAIDAAIAANAMEGLVEPHVNGIGGDLFAIVWDAKTKKLYGLNASGRSPYTLTLAELQKRGLKHIPSDGPLPVSVPGCVDGWFELHKRFGKAPMPSILSHAIRYAREGYPVHDEAAFYWPSMIARFGKYPNVNETYAPTGAAPKRGELFKNPALANTLDKIARGGRDAFYKGDIAKTIDAFMKKMGGYLSAKDLADHTSEWVEPVSTNYRGYDVWELPPNSQGIATLQMLNLLEGYDFSQTPWGSPEHIHRFIEAKKLAFEDRAKYYADPAFARIPVRELVSKAYATERRKLIDLNRAASRVEAGNPALKQGDTIYLTVADEEGNMVSLIQSNYRGFGSGMVPDGLGFMLQDRGELYSLIDGQNNTFAPHKRPFQTIIPAFITKDGQPFMSFGVMGGSFQPLGHVQIVMNMIDFGMNPQEAGDAPRIDHQGSSEPTGEKMMDSGQITLESGYPYETIRDLMRKGHKVGYGLGGYGGYQAIMYDAKNKIYHGATESRKDGQAAGF |
Post-translational modification
Cleaved by autocatalysis into a large and a small subunit.
Keywords
- PTM
Interaction
Subunit
This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 482-502 | Disordered | ||||
Sequence: AGDAPRIDHQGSSEPTGEKMM |
Sequence similarities
Belongs to the gamma-glutamyltransferase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length565
- Mass (Da)61,943
- Last updated2015-06-24 v1
- Checksum4A70B6734F9E2D91
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP010429 EMBL· GenBank· DDBJ | AKD56213.1 EMBL· GenBank· DDBJ | Genomic DNA |