A0A0E3P9X9 · A0A0E3P9X9_9EURY

  • Protein
    K(+)-insensitive pyrophosphate-energized proton pump
  • Gene
    hppA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for site.

167150100150200250300350400450500550600650
TypeIDPosition(s)Description
Site451Determinant of potassium independence

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functiondiphosphate hydrolysis-driven proton transmembrane transporter activity
Molecular Functioninorganic diphosphate phosphatase activity
Molecular Functionmagnesium ion binding

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    K(+)-insensitive pyrophosphate-energized proton pump
  • EC number
  • Alternative names
    • Membrane-bound proton-translocating pyrophosphatase
    • Pyrophosphate-energized inorganic pyrophosphatase
      (H(+)-PPase
      )

Gene names

    • Name
      hppA
    • ORF names
      MSSIT_3228

Organism names

  • Taxonomic identifier
  • Strain
    • T4/M
  • Taxonomic lineage
    Archaea > Euryarchaeota > Stenosarchaea group > Methanomicrobia > Methanosarcinales > Methanosarcinaceae > Methanosarcina

Accessions

  • Primary accession
    A0A0E3P9X9

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Endomembrane system
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane6-27Helical
Transmembrane55-73Helical
Transmembrane79-102Helical
Transmembrane122-140Helical
Transmembrane146-169Helical
Transmembrane224-243Helical
Transmembrane249-270Helical
Transmembrane282-304Helical
Transmembrane310-331Helical
Transmembrane393-413Helical
Transmembrane490-513Helical
Transmembrane558-576Helical
Transmembrane581-599Helical
Transmembrane649-670Helical

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    671
  • Mass (Da)
    69,070
  • Last updated
    2015-06-24 v1
  • MD5 Checksum
    A04474E9DC297D451747165912380690
MEGLIFIAPLAGVISLVFAAFFAKSILKEDAGNKRMKEIAGAIQEGAMAYLNRQYKTIAVVSIILSFLILFLLDDGLKIAIGFLAGAISSAAAGYIGMSVSVRANVRTAHAASSGLEKAMSVAFRGGAVTGLAVVGLALLGTSSFYILYGDVNLVVGFGFGASLISLFARVGGGIFTKAADVGADLVGKVEAGIPEDDPRNAGVIADNVGDNVGDCAGMGADLFETYVVTSLAAMLLGSLITGTYENAILYPLILGSVAIFASIISVFFVKIGKEGKIMQALYKGVGGSAIISLIAFYFVTNYLMGDIRLFYATLVGIVITVLMVIITEYYTSTDYRPVKTIAASSETGAATNIISGLSIGFESTLVPTVVIVIGILLSYFVVGGAADSGIGLYGIAIAAVAMLSTTGMIVALDSYGPITDNAGGIAQMANLPAQVRKVTDALDAVGNTTKAVTKGYAIGSAALGALALFADYRSKVNLGGQSLNLDDPVVLAGLLLGALLPFVFSAVTMSAVGKAAFEVVNEVRRQFREIPGIMEGTAKPEYGRCVDIVTKAALHEMAMPGFLAVLVPLLVGFILGPKALAGLLIGLIVVGFMLALMMDNGGGAWDNAKKLIEDGNHGGRGSEAHKAAVVGDTVGDPFKDTAGPALNALIKVVNMVAILFSALIIHSGLF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP009506
EMBL· GenBank· DDBJ
AKB29947.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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