A0A0E3P9X9 · A0A0E3P9X9_9EURY
- ProteinK(+)-insensitive pyrophosphate-energized proton pump
- GenehppA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids671 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.
Catalytic activity
- diphosphate + H2O + H+(in) = 2 phosphate + 2 H+(out)
Cofactor
Features
Showing features for site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Site | 451 | Determinant of potassium independence | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | diphosphate hydrolysis-driven proton transmembrane transporter activity | |
Molecular Function | inorganic diphosphate phosphatase activity | |
Molecular Function | magnesium ion binding |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameK(+)-insensitive pyrophosphate-energized proton pump
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageArchaea > Euryarchaeota > Stenosarchaea group > Methanomicrobia > Methanosarcinales > Methanosarcinaceae > Methanosarcina
Accessions
- Primary accessionA0A0E3P9X9
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Endomembrane system ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 6-27 | Helical | |||
Transmembrane | 55-73 | Helical | |||
Transmembrane | 79-102 | Helical | |||
Transmembrane | 122-140 | Helical | |||
Transmembrane | 146-169 | Helical | |||
Transmembrane | 224-243 | Helical | |||
Transmembrane | 249-270 | Helical | |||
Transmembrane | 282-304 | Helical | |||
Transmembrane | 310-331 | Helical | |||
Transmembrane | 393-413 | Helical | |||
Transmembrane | 490-513 | Helical | |||
Transmembrane | 558-576 | Helical | |||
Transmembrane | 581-599 | Helical | |||
Transmembrane | 649-670 | Helical | |||
Keywords
- Cellular component
Interaction
Subunit
Homodimer.
Structure
Sequence
- Sequence statusComplete
- Length671
- Mass (Da)69,070
- Last updated2015-06-24 v1
- MD5 ChecksumA04474E9DC297D451747165912380690
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP009506 EMBL· GenBank· DDBJ | AKB29947.1 EMBL· GenBank· DDBJ | Genomic DNA |