A0A0E3L7N4 · A0A0E3L7N4_9EURY

Function

Catalytic activity

Pathway

Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 2/4.
Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 2/3.
Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 2/5.

Features

Showing features for active site.

134250100150200250300
TypeIDPosition(s)Description
Active site149Acyl-thioester intermediate
Active site241Proton acceptor

GO annotations

AspectTerm
Molecular Functionaspartate-semialdehyde dehydrogenase activity
Molecular FunctionNAD binding
Molecular FunctionNADP binding
Molecular Functionprotein dimerization activity
Biological Processlysine biosynthetic process via diaminopimelate
Biological Processmethionine biosynthetic process
Biological Processthreonine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    aspartate-semialdehyde dehydrogenase
  • EC number

Gene names

    • ORF names
      MSSIT_0357

Organism names

  • Taxonomic identifier
  • Strain
    • T4/M
  • Taxonomic lineage
    Archaea > Euryarchaeota > Stenosarchaea group > Methanomicrobia > Methanosarcinales > Methanosarcinaceae > Methanosarcina

Accessions

  • Primary accession
    A0A0E3L7N4

Proteomes

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain5-130Semialdehyde dehydrogenase NAD-binding

Sequence similarities

Belongs to the aspartate-semialdehyde dehydrogenase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    342
  • Mass (Da)
    36,753
  • Last updated
    2015-06-24 v1
  • Checksum
    7F963F9DA4DC1430
MAAVKAGILGATGAVGQRFVEALANHPWFEITALAASERSAGKTYREAAGWRLDTAMPESVENIEVVPVDPKAVDADVVFSALPADLALTVEPEFAKAGFAVASNASSYRMEKDIPLVIPEVNPGHLGLLEVQQDIRGWDGYIITNPNCSTIVMTITLKPLMQFGLETVQVATMQAISGAGFSGVAAMAIYDNVIPYIGSEEKKMETETLKLLGEFNGSEIVPADMKVSASCHRVPVIDGHTEAIWAGMRDKPTPEEVRESFLKFDPKLGELPSEPGKALIVRDEVDRPQPRLDRNMGKGMSVSVGRIREGIRYIAMGHNTIRGAAGASVLNAELLHSMGKL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP009506
EMBL· GenBank· DDBJ
AKB27076.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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