A0A0E3JCP7 · A0A0E3JCP7_9CHIR
- ProteinPhosphoenolpyruvate carboxykinase, cytosolic [GTP]
- GenePck1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids606 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
Catalytic activity
- GTP + L-seryl-[protein] = GDP + H+ + O-phospho-L-seryl-[protein]This reaction proceeds in the forward direction.
Cofactor
Pathway
Carbohydrate biosynthesis; gluconeogenesis.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | GTP binding | |
Molecular Function | kinase activity | |
Molecular Function | manganese ion binding | |
Molecular Function | phosphoenolpyruvate carboxykinase (GTP) activity | |
Biological Process | cellular response to dexamethasone stimulus | |
Biological Process | cellular response to glucose stimulus | |
Biological Process | cellular response to insulin stimulus | |
Biological Process | dicarboxylic acid metabolic process | |
Biological Process | gluconeogenesis | |
Biological Process | glycerol biosynthetic process from pyruvate | |
Biological Process | hepatocyte differentiation | |
Biological Process | propionate catabolic process | |
Biological Process | response to starvation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhosphoenolpyruvate carboxykinase, cytosolic [GTP]
- EC number
- Alternative names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Chiroptera > Yinpterochiroptera > Rhinolophoidea > Hipposideridae > Hipposideros
Accessions
- Primary accessionA0A0E3JCP7
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Keywords
- PTM
Interaction
Subunit
Monomer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 21-248 | Phosphoenolpyruvate carboxykinase GTP-utilising N-terminal | ||||
Sequence: EFVEQNARLCQPDHIHICDGSEEENRQLLHQMEEQGTIKRLKKYDNCWLALTDPRDVARIESKTVIITQEQRDTVPISKNGQSQLGRWMSEGDFEKAFNARFPGCMKGRTMYVIPFSMGPLGSPLAKIGIELSDSPYVVASMRIMTRMGTPILEALGDGEFIKCLHSVGCPLPLKKPLVNNWACNPELTLIAHLPDRREIISFGSGYGGNSLLGKKCFALRIASRLAK | ||||||
Domain | 252-603 | Phosphoenolpyruvate carboxykinase C-terminal P-loop | ||||
Sequence: WLAEHMLILGITNPEGQKKYFAAAFPSACGKTNLAMMNPTLPGWKVECVGDDIAWMKFDQQGNLRAINPENGFFGVAPGTSVKTNPNAIKTIQKNTIFTNVAETSDGGIYWEGIDQPLASGIKLTSWKNKEWAPEDGEPCAHPNSRFCTPASQCPIMDPAWEAPEGVPIEGIIFGGRRPAGVPLVYEALNWQHGVFVGAAMRSEATAAAEHKGKVIMHDPFAMRPFFGYNFGKYLAHWLSMAQRPAAKLPKIFHVNWFRKDKEGKFLWPGFGENSRVLEWMFNRIDGKGGAKLTAIGYIPEEGALNLKGLGDINMKELFDISKEFWEKEAEDIQTYLEEQVNADLPYEIERE |
Sequence similarities
Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
Family and domain databases
Sequence
- Sequence statusFragment
- Length606
- Mass (Da)67,510
- Last updated2015-06-24 v1
- Checksum1893F28ABCFA17B6
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: L | ||||||
Non-terminal residue | 606 | |||||
Sequence: A |