A0A0E2ZKY6 · A0A0E2ZKY6_9GAMM

  • Protein
    Pimeloyl-[acyl-carrier protein] methyl ester esterase
  • Gene
    bioH
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Pathway

Cofactor biosynthesis; biotin biosynthesis.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site20substrate
Active site81Nucleophile
Binding site81-82substrate
Binding site143-147substrate
Active site207
Active site235
Binding site235substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionpimelyl-[acyl-carrier protein] methyl ester esterase activity
Biological Processbiotin biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Pimeloyl-[acyl-carrier protein] methyl ester esterase
  • EC number
  • Alternative names
    • Biotin synthesis protein BioH
    • Carboxylesterase BioH

Gene names

    • Name
      bioH
    • ORF names
      IB75_11190

Organism names

  • Taxonomic identifier
  • Strain
    • C-27
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Chromatiales > Chromatiaceae > Nitrosococcus

Accessions

  • Primary accession
    A0A0E2ZKY6

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Monomer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain14-241AB hydrolase-1

Sequence similarities

Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    255
  • Mass (Da)
    27,577
  • Last updated
    2015-05-27 v1
  • Checksum
    A4225A8CCB593875
MTLQIVQRGAGPDLVLLHGWGFHSGVWAPLVDCLSTRFRLTLVDLPGHGGSDPLAQGRRLAAVAETVARVAPPQACWLGWSLGGLVALQAAIDFPRRVNKLVLVASTPRFVTAVDWPYGVAPEVLADFSVALQNDSVETLKRFVWLQTRGAERAKAVAQVLLAHFNAPYRPGIEGLEDGLALLQDSDLRVELETIPCPTLAIMGQRDPLVPPKVGAWLSAHLPQGQVFMIPRAGHAPFLSHGQVFKDIVSNFLQA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JPGN01000069
EMBL· GenBank· DDBJ
KFI18982.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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