A0A0E2H3P9 · A0A0E2H3P9_9FIRM

Function

function

Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na+ movement across the membrane.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Activity regulation

Requires K+ for maximal activity.

Features

Showing features for site.

TypeIDPosition(s)Description
Site441Determinant of potassium dependence

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functiondiphosphate hydrolysis-driven proton transmembrane transporter activity
Molecular Functioninorganic diphosphate phosphatase activity
Molecular Functionmagnesium ion binding
Molecular Functionpotassium ion binding
Biological Processsodium ion transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Putative K(+)-stimulated pyrophosphate-energized sodium pump
  • EC number
  • Alternative names
    • Membrane-bound sodium-translocating pyrophosphatase
    • Pyrophosphate-energized inorganic pyrophosphatase
      (Na(+)-PPase
      )

Gene names

    • Name
      hppA
    • ORF names
      HMPREF1090_04739

Organism names

Accessions

  • Primary accession
    A0A0E2H3P9

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Endomembrane system
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane6-26Helical
Transmembrane47-70Helical
Transmembrane76-101Helical
Transmembrane122-148Helical
Transmembrane154-171Helical
Transmembrane224-242Helical
Transmembrane248-271Helical
Transmembrane283-303Helical
Transmembrane309-330Helical
Transmembrane351-376Helical
Transmembrane382-403Helical
Transmembrane442-463Helical
Transmembrane475-498Helical
Transmembrane546-564Helical
Transmembrane570-589Helical
Transmembrane637-654Helical

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    660
  • Mass (Da)
    68,042
  • Last updated
    2015-05-27 v1
  • Checksum
    BAD901CE7B5574A3
MEQMLFLVPVVGLLGLLFAVILRQQIVKEDPGTDRMREIADAIAEGANAFLASEYRILVVFVAVLFFVIGFGTRNWITAGCFLVGSGFSTMAGYLGMNAAIRANSRTADAARISGMHRALALAFSGGSVMGMAVVGLGLLGVGVLYILTRDVSVLSGFSLGASSIALFARVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDVAGMGADLFESYVGSLISALTLGLVFYQEAGIVFPLMLSACGIIAAIIGSLLVKSIGSSDPHKALKTGEYSATALVVVCSLVLSRIFFGNFMAAFTIITGLLVGVLIGAVTEIYTSGDYRFVKKIAGQSETGSATTIISGIAVGMQSTAVPILLVCVGVLISNKLMGLYGIALAAVGMLSTTGITVAIDAYGPIADNAGGIAEMAGLDKNVRDITDKLDSVGNTTAAIGKGFAIGSAALTALALFVSYAEAVKLTTIDILNAHVIVGLFIGGMLTFLFSAMTMESVSKAAHQMIEEVRRQFREKPGILKGTDRPDYASCVSISTKAALREMFLPGLMAVLAPLATGLILGPSALGGLLTGALVTGVLMAIFMSNSGGAWDNAKKYIEEGHHGGKGSDSHKAAVVGDTVGDPFKDTSGPSINILIKLMTIVSLVFAPLFLRFGGLI

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AGYR01000058
EMBL· GenBank· DDBJ
ENZ08883.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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