A0A0E0Y8D9 · A0A0E0Y8D9_ECO1C

Function

function

Catalyzes the decarboxylation of 3-keto-L-gulonate-6-P into L-xylulose-5-P. Is involved in the anaerobic L-ascorbate utilization.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 1 Mg2+ ion per subunit.

Pathway

Cofactor degradation; L-ascorbate degradation; D-xylulose 5-phosphate from L-ascorbate: step 2/4.

Features

Showing features for binding site, site.

Type
IDPosition(s)Description
Binding site11substrate
Binding site33Mg2+ (UniProtKB | ChEBI)
Binding site62Mg2+ (UniProtKB | ChEBI)
Site64Transition state stabilizer
Site67Transition state stabilizer
Binding site192substrate

GO annotations

AspectTerm
Molecular Function3-dehydro-L-gulonate-6-phosphate decarboxylase activity
Molecular Functionmagnesium ion binding
Molecular Functionorotidine-5'-phosphate decarboxylase activity
Biological Process'de novo' pyrimidine nucleobase biosynthetic process
Biological ProcessL-ascorbic acid catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    3-keto-L-gulonate-6-phosphate decarboxylase UlaD
  • EC number
  • Alternative names
    • 3-dehydro-L-gulonate-6-phosphate decarboxylase
    • KGPDC
    • L-ascorbate utilization protein D

Gene names

    • Name
      ulaD
    • Ordered locus names
      O3K_22660

Organism names

Accessions

  • Primary accession
    A0A0E0Y8D9

Proteomes

Expression

Induction

Induced by L-ascorbate. Repressed by UlaR.

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain5-207Orotidine 5'-phosphate decarboxylase

Sequence similarities

Belongs to the HPS/KGPDC family. KGPDC subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    216
  • Mass (Da)
    23,649
  • Last updated
    2015-05-27 v1
  • MD5 Checksum
    5FFD296BCA997AA129609D699EEC071B
MSLPMLQVALDNQTMDSAYETTRLIAEEVDIIEVGTILCVGEGVRAVRDLKALYPHKIVLADAKIADAGKILSRMCFEANADWVTVICCADINTAKGALDVAKEFNGDVQIELTGYWTWEQAQQWRDAGIQQVVYHRSRDAQAAGVAWGEADITAIKRLSDMGFKVTVTGGLALEDLPLFKGIPIHVFIAGRSIRDAASPVEAARQFKRSIAELWG

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP003289
EMBL· GenBank· DDBJ
AFS76386.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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