A0A0E0FBG8 · A0A0E0FBG8_9ORYZ

  • Protein
    Telomerase reverse transcriptase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.

Catalytic activity

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentchromosome, telomeric region
Cellular Componenttelomerase catalytic core complex
Molecular Functionmetal ion binding
Molecular FunctionRNA-directed DNA polymerase activity
Molecular Functiontelomerase RNA binding
Molecular Functiontelomeric DNA binding
Biological Processtelomere maintenance via telomerase

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Telomerase reverse transcriptase
  • EC number
  • Alternative names
    • Telomerase catalytic subunit

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • OR44
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Poaceae > BOP clade > Oryzoideae > Oryzeae > Oryzinae > Oryza

Accessions

  • Primary accession
    A0A0E0FBG8

Proteomes

Genome annotation databases

Subcellular Location

Keywords

Family & Domains

Features

Showing features for compositional bias, region, domain.

Type
IDPosition(s)Description
Compositional bias1-16Basic and acidic residues
Region1-53Disordered
Compositional bias19-42Polar residues
Domain393-676Reverse transcriptase

Sequence similarities

Belongs to the reverse transcriptase family. Telomerase subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    868
  • Mass (Da)
    99,200
  • Last updated
    2015-05-27 v1
  • Checksum
    FD5336D3524EF024
MEVEEAESHGRAVRRAGDPNVESSTSGSTDDAPLQNPASNGQKPPIPLSPTGPLRCRLVLHPPHFPVAMPRRRRRRAAPGGQVPPELRLAYGARALTLGRAVFSLLPSPRHRESPCPACRGRVASGCLACRRWEHLLRDGDPVAYRRLITRAVCAIAADDLSAPPPPRYTPGNSGHSQARLVREMMKSIVADQSHGTKNVLCNGLHEGGQSICISDLVSSSSWSILLHRIGDLLMCYLLRCTSIFLPVSGVPLNVVLRNPIFASTVARKHQPQTTKAKCHTVAPDVTKNDGKAHYPPGGKAAYYDRSFSRLEAYSTHQQVASFVWAVLKRIVPKPLLGNSFGKRSLRTNIWKFIKLQRESKRYDVFYYPKSVWRDLTSNAIASLNKKNFRILRGEPRKAVRHLNCSSRVRFLPKAKDMRPLVNLRAKSKDANLNKCHLIMKKLRDEKPEMFGSSVFDYNNVHQNLSQFISSKRSQLMKKLKVYIVVADVSKAFDCVSHDMVLKMIDDAFKCDEYTVRKCSKGTICRVLKEQFHHLLYEQIKCNILKIGQKYYLQQVGIAQGSKLSPNLCSLYYGHLENSVLSKFLHDSKLNAGEAFSEPEYLLMRFIDDFIFISFSLEHAQKFLNRMRRGFVFYNCYMNDSKYGFNFCAGNSEPSSNRLYRGDDGVSFMPWSGLLINCETLEIQADYTRYLDITIISTITVKMHSSTKYIHSKLCHYMRPKCHPIFYDSNINSPGTIRVNIYQAFLLCAMKFHCYIRSISDANVSKLELLQVIKRTFRYMHSLIVRRMQDVELHYNVRPVLKLRRKETIWLGLTAYIRVLQQKQSRYKDMLTLLTAELGRYCHLGHECDTLRYAVDDSHSSMFWKFKF

Computationally mapped potential isoform sequences

There are 5 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A0E0FBG3A0A0E0FBG3_9ORYZ1141
A0A0E0FBG4A0A0E0FBG4_9ORYZ1052
A0A0E0FBG5A0A0E0FBG5_9ORYZ992
A0A0E0FBG6A0A0E0FBG6_9ORYZ1104
A0A0E0FBG7A0A0E0FBG7_9ORYZ1041

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1-16Basic and acidic residues
Compositional bias19-42Polar residues

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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