A0A0D9SEY3 · A0A0D9SEY3_HUMAN
- ProteinPotassium sodium-activated channel subfamily T member 1
- GeneKCNT1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1237 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score1/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Molecular Function | potassium channel activity |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionA0A0D9SEY3
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 98-117 | Helical | ||||
Sequence: LFNFSLKLLTCLLYIVRVLL | ||||||
Transmembrane | 155-176 | Helical | ||||
Sequence: MTLWAIQVIVAIISFLETMLLI | ||||||
Transmembrane | 252-273 | Helical | ||||
Sequence: VLILFCTLLCLVFTGTCGIQHL | ||||||
Transmembrane | 279-298 | Helical | ||||
Sequence: NLSLLTSFYFCIVTFSTVGY | ||||||
Transmembrane | 310-335 | Helical | ||||
Sequence: LLVVIMICVALVVLPLQFEELVYLWM |
Keywords
- Cellular component
Disease & Variants
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 1,529 variants from UniProt as well as other sources including ClinVar and dbSNP.
Genetic variation databases
PTM/Processing
Proteomic databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for region, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-37 | Disordered | ||||
Sequence: MARAKLPRSPSEGKAGPGGAPAGAAAPEEPHGLSPLL | ||||||
Domain | 260-327 | Potassium channel | ||||
Sequence: LCLVFTGTCGIQHLERAGENLSLLTSFYFCIVTFSTVGYGDVTPKIWPSQLLVVIMICVALVVLPLQF | ||||||
Domain | 485-579 | Calcium-activated potassium channel BK alpha subunit | ||||
Sequence: DHVVCEEECKYAMLALNCICPATSTLITLLVHTSRGQEGQESPEQWQRMYGRCSGNEVYHIRMGDSKFFREYEGKSFTYAAFHAHKKYGVCLIGL | ||||||
Region | 660-689 | Disordered | ||||
Sequence: TEHRPTQSGGGGGGSKLALPTENGSGSRRP | ||||||
Region | 1051-1085 | Disordered | ||||
Sequence: EDTREVKGPWGSRAGTGGSSQGRHTGGGDPAEHPL | ||||||
Region | 1211-1237 | Disordered | ||||
Sequence: SSSQSRKSSCSHKLSSCNPETRDETQL |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,237
- Mass (Da)139,161
- Last updated2015-05-27 v1
- ChecksumB579FF35A1DA3FBE
Computationally mapped potential isoform sequences
There are 13 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
Q5JUK3 | KCNT1_HUMAN | KCNT1 | 1230 | ||
C9J9Y7 | C9J9Y7_HUMAN | KCNT1 | 1217 | ||
A0A0R4J2E0 | A0A0R4J2E0_HUMAN | KCNT1 | 1223 | ||
A0A6Q8PFI9 | A0A6Q8PFI9_HUMAN | KCNT1 | 1151 | ||
A0A6Q8PFE8 | A0A6Q8PFE8_HUMAN | KCNT1 | 1203 | ||
A0A6Q8PFS3 | A0A6Q8PFS3_HUMAN | KCNT1 | 1172 | ||
A0A6Q8PGM3 | A0A6Q8PGM3_HUMAN | KCNT1 | 1175 | ||
F8WC49 | F8WC49_HUMAN | KCNT1 | 122 | ||
C9JYL2 | C9JYL2_HUMAN | KCNT1 | 1216 | ||
C9JBV2 | C9JBV2_HUMAN | KCNT1 | 285 | ||
C9JAX7 | C9JAX7_HUMAN | KCNT1 | 1235 | ||
A0A0D9SFR1 | A0A0D9SFR1_HUMAN | KCNT1 | 177 | ||
A0A0D9SFC8 | A0A0D9SFC8_HUMAN | KCNT1 | 1201 |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AL158822 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |