A0A0D8KJM2 · A0A0D8KJM2_9HYPH

  • Protein
    D-malate dehydrogenase [decarboxylating]
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    4/5

Function

function

Has multiple catalytic activities. Apart from catalyzing the oxidation of +-tartrate to oxaloglycolate, also converts meso-tartrate to D-glycerate and catalyzes the oxidative decarboxylation of D-malate to pyruvate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
K+ (UniProtKB | Rhea| CHEBI:29103 )

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Pathway

Carbohydrate acid metabolism; tartrate degradation; 2-hydroxy-3-oxosuccinate from L-tartrate: step 1/1.
Carbohydrate acid metabolism; tartrate degradation; 2-hydroxy-3-oxosuccinate from meso-tartrate: step 1/1.
Carbohydrate acid metabolism; tartrate degradation; D-glycerate from L-tartrate: step 1/1.

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionD-malate dehydrogenase (decarboxylating) (NAD+) activity
Molecular Functionmagnesium ion binding
Molecular FunctionNAD binding
Molecular Functiontartrate decarboxylase activity
Molecular Functiontartrate dehydrogenase activity

Keywords

  • Molecular function
  • Ligand

Enzyme and pathway databases

Names & Taxonomy

Protein names

Gene names

    • ORF names
      RS75_04090

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • 39/7
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Rhizobiaceae > Rhizobium/Agrobacterium group > Rhizobium

Accessions

  • Primary accession
    A0A0D8KJM2

Proteomes

Subcellular Location

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain5-342Isopropylmalate dehydrogenase-like

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    347
  • Mass (Da)
    36,961
  • Last updated
    2015-05-27 v1
  • Checksum
    8DD1BC0F5AA35678
MKTHRIALIPGDGIGRSVTEAAWQVLNAAAKSSNFALEGTEFPWSCAFYKETGAMMPKDGIETLRGFDAVMLGAVGWPAEVPDSVSLHGLLLPIRKAFVQYANIRPHRLLPGVQGPLKSDGFDILCIRENTEGEYSGAGGRVHQGTGDEVAVETSIFTRKGVERILRFGFEQAQKRRGKLASVTKSNAQKYSMVFWDEVTQKLADEYPDVEVSSYHIDAMAARMVMAPESLDVVVASNLFGDILTDLGAAIQGGLGFAASANINPDRSAPSMFEPVHGSAPDIAHLGIANPIAAIWSGAMMFEHLGETDAAAKIMTALETATGRGIGTVPGKDKTDTITAAILAALD

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JWJH01000003
EMBL· GenBank· DDBJ
KJF69156.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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