A0A0D8KJM2 · A0A0D8KJM2_9HYPH
- ProteinD-malate dehydrogenase [decarboxylating]
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids347 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
function
Has multiple catalytic activities. Apart from catalyzing the oxidation of +-tartrate to oxaloglycolate, also converts meso-tartrate to D-glycerate and catalyzes the oxidative decarboxylation of D-malate to pyruvate.
Catalytic activity
- (2R,3R)-tartrate + H+ = (R)-glycerate + CO2
Cofactor
Protein has several cofactor binding sites:
Pathway
Carbohydrate acid metabolism; tartrate degradation; 2-hydroxy-3-oxosuccinate from L-tartrate: step 1/1.
Carbohydrate acid metabolism; tartrate degradation; 2-hydroxy-3-oxosuccinate from meso-tartrate: step 1/1.
Carbohydrate acid metabolism; tartrate degradation; D-glycerate from L-tartrate: step 1/1.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | D-malate dehydrogenase (decarboxylating) (NAD+) activity | |
Molecular Function | magnesium ion binding | |
Molecular Function | NAD binding | |
Molecular Function | tartrate decarboxylase activity | |
Molecular Function | tartrate dehydrogenase activity |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameD-malate dehydrogenase [decarboxylating]
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Rhizobiaceae > Rhizobium/Agrobacterium group > Rhizobium
Accessions
- Primary accessionA0A0D8KJM2
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 5-342 | Isopropylmalate dehydrogenase-like | ||||
Sequence: RIALIPGDGIGRSVTEAAWQVLNAAAKSSNFALEGTEFPWSCAFYKETGAMMPKDGIETLRGFDAVMLGAVGWPAEVPDSVSLHGLLLPIRKAFVQYANIRPHRLLPGVQGPLKSDGFDILCIRENTEGEYSGAGGRVHQGTGDEVAVETSIFTRKGVERILRFGFEQAQKRRGKLASVTKSNAQKYSMVFWDEVTQKLADEYPDVEVSSYHIDAMAARMVMAPESLDVVVASNLFGDILTDLGAAIQGGLGFAASANINPDRSAPSMFEPVHGSAPDIAHLGIANPIAAIWSGAMMFEHLGETDAAAKIMTALETATGRGIGTVPGKDKTDTITAAI |
Sequence similarities
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length347
- Mass (Da)36,961
- Last updated2015-05-27 v1
- Checksum8DD1BC0F5AA35678
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JWJH01000003 EMBL· GenBank· DDBJ | KJF69156.1 EMBL· GenBank· DDBJ | Genomic DNA |