A0A0D8JVP4 · A0A0D8JVP4_COCIM
- ProteinGMP synthase (glutamine-hydrolyzing)
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids500 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
function
Catalyzes the conversion of xanthine monophosphate (XMP) to GMP in the presence of glutamine and ATP through an adenyl-XMP intermediate.
Catalytic activity
- XMP + L-glutamine + ATP + H2O = GMP + L-glutamate + AMP + diphosphate + 2 H+
Pathway
Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1.
Features
Showing features for active site, binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | ATP binding | |
Molecular Function | GMP synthase activity | |
Biological Process | glutamine metabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGMP synthase (glutamine-hydrolyzing)
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Eurotiomycetes > Eurotiomycetidae > Onygenales > Onygenaceae > Coccidioides
Accessions
- Primary accessionA0A0D8JVP4
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 171-375 | GMPS ATP-PPase | ||||
Sequence: WTMAKFVDQEITRIRKLVGETDHVLGAVSGGVDSTVASKLMKEAIGDRFHAVLVNNGCMRLNECEQVHETLGKHLGINLTVVDASKQFLDALKGVTDPERKRKIIGGKFIDVFEAEALKIEAGVKHTGAKVKWFLQGTLYPDVIESLSFKGPSATIKTHHNVGGLPKRMQEGAGLKLIEPLRELFKDEVRQLGRELGIHNDLVMR |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length500
- Mass (Da)55,109
- Last updated2015-05-27 v1
- Checksum5235821532AD9B9D
Computationally mapped potential isoform sequences
There are 2 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A0D8JW98 | A0A0D8JW98_COCIM | CIMG_09582 | 539 | ||
A0A0D8JWU1 | A0A0D8JWU1_COCIM | CIMG_09582 | 524 |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
GG704915 EMBL· GenBank· DDBJ | KJF61400.1 EMBL· GenBank· DDBJ | Genomic DNA |