A0A0D7KDF6 · A0A0D7KDF6_9BURK
- ProteinQuinone-dependent D-lactate dehydrogenase
- Genedld
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids585 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the oxidation of D-lactate to pyruvate.
Catalytic activity
- (R)-lactate + a quinone = a quinol + pyruvate
Cofactor
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 76-80 | FAD (UniProtKB | ChEBI) | ||||
Sequence: AANTG | ||||||
Binding site | 84-85 | FAD (UniProtKB | ChEBI) | ||||
Sequence: GS | ||||||
Binding site | 143 | FAD (UniProtKB | ChEBI) | ||||
Sequence: G | ||||||
Binding site | 150 | FAD (UniProtKB | ChEBI) | ||||
Sequence: S | ||||||
Binding site | 160 | FAD (UniProtKB | ChEBI) | ||||
Sequence: G | ||||||
Binding site | 258 | FAD (UniProtKB | ChEBI) | ||||
Sequence: A | ||||||
Binding site | 263 | FAD (UniProtKB | ChEBI) | ||||
Sequence: L |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | extrinsic component of cytoplasmic side of plasma membrane | |
Molecular Function | D-lactate dehydrogenase (quinone) activity | |
Molecular Function | FAD binding | |
Molecular Function | quinone binding | |
Biological Process | lactate oxidation | |
Biological Process | respiratory electron transport chain | |
Biological Process | transmembrane transport |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameQuinone-dependent D-lactate dehydrogenase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Comamonadaceae > Acidovorax
Accessions
- Primary accessionA0A0D7KDF6
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell inner membrane ; Peripheral membrane protein
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 42-221 | FAD-binding PCMH-type | ||||
Sequence: GEGPVLAVVRPGTLLEQWKVLQAAVAAGRIVIMQAANTGLTGGSTPDGANYDREIVLVNTLRITGVQVIAGGEQVVCLPGATLDKLEQTLAPLGREPHSVIGSSCIGASVLGGICNNSGGALVRRGPAYTELALYARVKDDGTLELVNHLGIALGNTPEEILTRLQNGDYVEADVERDTG |
Sequence similarities
Belongs to the quinone-dependent D-lactate dehydrogenase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length585
- Mass (Da)64,547
- Last updated2015-05-27 v1
- Checksum84E59754619A7424
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JXYQ01000008 EMBL· GenBank· DDBJ | KJA12012.1 EMBL· GenBank· DDBJ | Genomic DNA |