A0A0D6QPN8 · A0A0D6QPN8_9BACT

  • Protein
    NADPH-dependent 7-cyano-7-deazaguanine reductase
  • Gene
    queF
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

tRNA modification; tRNA-queuosine biosynthesis.

Features

Showing features for active site, binding site.

Type
IDPosition(s)Description
Active site34Thioimide intermediate
Active site41Proton donor
Binding site56-58substrate
Binding site75-76substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionpreQ1 synthase activity
Biological Processqueuosine biosynthetic process
Biological ProcesstRNA modification

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADPH-dependent 7-cyano-7-deazaguanine reductase
  • EC number
  • Alternative names
    • 7-cyano-7-carbaguanine reductase
    • NADPH-dependent nitrile oxidoreductase
    • PreQ(0) reductase

Gene names

    • Name
      queF
    • ORF names
      PSR1_04229

Organism names

  • Taxonomic identifier
  • Strain
    • PSR-1
  • Taxonomic lineage
    Bacteria > Myxococcota > Myxococcia > Myxococcales > Cystobacterineae > Anaeromyxobacteraceae > Anaeromyxobacter

Accessions

  • Primary accession
    A0A0D6QPN8

Proteomes

Subcellular Location

Keywords

Family & Domains

Sequence similarities

Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    122
  • Mass (Da)
    13,673
  • Last updated
    2015-05-27 v1
  • Checksum
    5BC81A29C676FBC3
MPTQPSRDLQTFPNPKPGRPFEIAMECPEFTCVCPMTGQPDFATIRLRYVPAERCVELKSLKLYLWSFRDEGTFHEAVTNRICDDLVAALAPRWIEVVGDFAVRGGIHTVVTARHGEKPAGV

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BAZG01000247
EMBL· GenBank· DDBJ
GAO05320.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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