A0A0D6I812 · A0A0D6I812_SALTM
- ProteinAlpha-1,4 glucan phosphorylase
- GenemalP_2
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids815 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
Catalytic activity
- [(1->4)-alpha-D-glucosyl](n) + phosphate = [(1->4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate
[(1→4)-α-D-glucosyl](n) RHEA-COMP:9584 + CHEBI:43474 = [(1→4)-α-D-glucosyl](n-1) RHEA-COMP:9586 + CHEBI:58601
Cofactor
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Molecular Function | glycogen phosphorylase activity | |
Molecular Function | linear malto-oligosaccharide phosphorylase activity | |
Molecular Function | pyridoxal phosphate binding | |
Molecular Function | SHG alpha-glucan phosphorylase activity | |
Biological Process | carbohydrate metabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAlpha-1,4 glucan phosphorylase
- EC number
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Salmonella
Accessions
- Primary accessionA0A0D6I812
- Secondary accessions
Proteomes
PTM/Processing
Features
Showing features for modified residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Modified residue | 662 | N6-(pyridoxal phosphate)lysine | ||||
Sequence: K |
Structure
Sequence
- Sequence statusComplete
- Length815
- Mass (Da)93,343
- Last updated2015-05-27 v1
- Checksum4464A9CBB044F1C2
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP011428 EMBL· GenBank· DDBJ | AKH09164.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHDPU010000009 EMBL· GenBank· DDBJ | EBU9272898.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHIDF010000006 EMBL· GenBank· DDBJ | EBW3627930.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHIPE010000011 EMBL· GenBank· DDBJ | EBW5463193.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHNIA010000002 EMBL· GenBank· DDBJ | EBY1700767.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAHRYM010000003 EMBL· GenBank· DDBJ | EBZ6920280.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAIGQE010000003 EMBL· GenBank· DDBJ | ECE0294748.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAIKGB010000001 EMBL· GenBank· DDBJ | ECF1541925.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAKRET010000007 EMBL· GenBank· DDBJ | ECU8353703.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAKUOT010000005 EMBL· GenBank· DDBJ | ECV8760070.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAKVET010000005 EMBL· GenBank· DDBJ | ECW0640286.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AALDNI010000008 EMBL· GenBank· DDBJ | ECY5340711.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAMLUT010000005 EMBL· GenBank· DDBJ | EDI6665133.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAAFPQ010000010 EMBL· GenBank· DDBJ | HAB0971733.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
DAANAV010000004 EMBL· GenBank· DDBJ | HAC9070190.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JYVU01000013 EMBL· GenBank· DDBJ | KTZ14029.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
RSUA01000001 EMBL· GenBank· DDBJ | MIT47449.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
RVDJ01000010 EMBL· GenBank· DDBJ | MLP86011.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
PHGX01000020 EMBL· GenBank· DDBJ | PJH62883.1 EMBL· GenBank· DDBJ | Genomic DNA |