A0A0D6AL89 · A0A0D6AL89_9CHRO

Function

function

Catalyzes the biosynthesis of agmatine from arginine.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

pyridoxal 5'-phosphate (UniProtKB | Rhea| CHEBI:597326 )

Pathway

Amine and polyamine biosynthesis; agmatine biosynthesis; agmatine from L-arginine: step 1/1.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site285-295substrate
Active site501Proton donor

GO annotations

AspectTerm
Molecular Functionarginine decarboxylase activity
Molecular Functionmetal ion binding
Biological Processarginine catabolic process
Biological Processspermidine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Biosynthetic arginine decarboxylase
  • EC number
  • Short names
    ADC

Gene names

    • Name
      speA
    • ORF names
      GM3709_356

Organism names

  • Taxonomic identifier
  • Strain
    • NIES-3709
  • Taxonomic lineage
    Bacteria > Cyanobacteriota > Cyanophyceae > Oscillatoriophycideae > Chroococcales > Geminocystaceae > Geminocystis

Accessions

  • Primary accession
    A0A0D6AL89

Proteomes

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue100N6-(pyridoxal phosphate)lysine

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain93-344Orn/DAP/Arg decarboxylase 2 N-terminal
Domain369-451Arginine decarboxylase helical bundle
Domain591-644Arginine decarboxylase C-terminal helical

Sequence similarities

Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    645
  • Mass (Da)
    73,792
  • Last updated
    2015-05-27 v1
  • Checksum
    AD7DCB8F6E2FB869
MTKFWTIEDSNKLYQIEGWGEPYFSINAEGNIVVSTRGDEHKIDLFELVESLKKRDINLPLLIRFSDMLDDRLKRLHDCMNEAIDRYNYNNVYRGVYPIKCNQHKQLVEALVEYGKPYNFGLEVGSKPELMIALATLEVDKNRERLLICNGYKDEEYLETALLAQQLGHNLIIVIEQISELFIILKLAQKLNLKPQLGVRAKLQTKGSGHWGNSTGEKAKFGLTIPEILTVINKLKSEDKLDCLKLLHFHIGSQISSIAVIKDAIREASQIYVQLSKMGAGMKYLDVGGGLAVDYDGSKTNFYASKNYNMQNYANDIVAAVKEACDENNISSPILVSESGRAITSHHSVLIFNVVSSNNPPLELPQPTEEKEHLIIRNLWETYETINEDNYQEMYHDAVQFKDEAISLFNFGYLTLIDRAKAEQLYWGCCHKIYQITKNEAYVSDDLNDLNDLMIATYYINLSVFQSAPDAWAIDQLFPILPIHRLNEKPTIKGVLADLTCDSDGKIDKFIDLLDVKNALELHPLKPIKEQDIDNPENTDFKPYYLGMFLVGAYQEIMGNLHNLFGDINVIHIQSKKENYQIKYVVKGDTVTDVLKYVEYSAEDLTEKLRCLTENALLEKQIDLEKSQLLIKNYEENLRGYTYLS

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP014821
EMBL· GenBank· DDBJ
BAQ63591.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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